Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TLR4 | O00206 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10762955 | 0.92 | MAPT (0.49) | ALDH1A1LMNAMAPTCYP2C9SLC18A3 | |
| SCHEMBL19647610 | 0.92 | ALDH1A1 (0.58) | ALDH1A1LMNAMAPTCYP2C9SLC18A3 | |
| SCHEMBL10765235 | 0.91 | MAPT (0.48) | ALDH1A1LMNAMAPTCYP2C9SLC18A3 | |
| SCHEMBL10766591 | 0.90 | LMNA (0.47) | ALDH1A1LMNAMAPTCYP2C9SLC18A3 | |
| SCHEMBL10761804 | 0.89 | SLC18A3 (0.50) | ALDH1A1LMNAMAPTCYP2C9SLC18A3 | |
| SCHEMBL19854501 | 0.83 | ALDH1A1 (0.56) | ALDH1A1LMNAMAPTCYP2C9SLC18A3 | |
| SCHEMBL9159105 | 0.82 | CYP2C9 (0.63) | ALDH1A1LMNAMAPTCYP2C9KMT2A | |
| SCHEMBL9159110 | 0.82 | CYP2C9 (0.63) | ALDH1A1LMNAMAPTCYP2C9KMT2A | |
| SCHEMBL5868999 | 0.82 | SLC18A3 (0.63) | ALDH1A1MAPTSLC18A3KMT2AMEN1 | |
| SCHEMBL9159091 | 0.82 | CYP2C9 (0.63) | ALDH1A1LMNAMAPTCYP2C9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0094487-B1 | HYDROTERPHENYLS, THEIR PREPARATION AND THEIR USE IN DIELECTRIC LIQUID CRYSTAL MATERIAL | MERCK PATENT GmbH (DE) | 1987-09-09 | — | — | EP | disclosed |
| US-4620938-A | Hydroterphenyls | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1986-11-04 | — | — | US | disclosed |
| EP-0094487-A1 | Hydroterphenyls, their preparation and their use in dielectric liquid crystal material | MERCK PATENT GmbH (DE) | 1983-11-23 | — | — | EP | disclosed |