Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10766591 | 0.99 | LMNA (0.47) | MAPTLMNAALDH1A1CYP2C9SLC18A3 | |
| SCHEMBL10762955 | 0.96 | MAPT (0.49) | MAPTLMNAALDH1A1CYP2C9SLC18A3 | |
| SCHEMBL10765895 | 0.91 | ALDH1A1 (0.58) | MAPTLMNAALDH1A1CYP2C9SLC18A3 | |
| SCHEMBL19856067 | 0.88 | MAPT (0.44) | MAPTLMNAALDH1A1CYP2C9SLC18A3 | |
| SCHEMBL19853814 | 0.88 | MAPT (0.44) | MAPTLMNAALDH1A1CYP2C9SLC18A3 | |
| SCHEMBL19856064 | 0.87 | MAPT (0.44) | MAPTLMNAALDH1A1CYP2C9SLC18A3 | |
| SCHEMBL19856062 | 0.87 | MAPT (0.44) | MAPTLMNAALDH1A1CYP2C9SLC18A3 | |
| SCHEMBL19853799 | 0.87 | MAPT (0.44) | MAPTLMNAALDH1A1CYP2C9SLC18A3 | |
| SCHEMBL19853806 | 0.87 | MAPT (0.44) | MAPTLMNAALDH1A1CYP2C9SLC18A3 | |
| SCHEMBL19856059 | 0.86 | THRA (0.51) | MAPTLMNAALDH1A1CYP2C9GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0094487-B1 | HYDROTERPHENYLS, THEIR PREPARATION AND THEIR USE IN DIELECTRIC LIQUID CRYSTAL MATERIAL | MERCK PATENT GmbH (DE) | 1987-09-09 | — | — | EP | disclosed |
| US-4620938-A | Hydroterphenyls | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1986-11-04 | — | — | US | disclosed |
| EP-0094487-A1 | Hydroterphenyls, their preparation and their use in dielectric liquid crystal material | MERCK PATENT GmbH (DE) | 1983-11-23 | — | — | EP | disclosed |