Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.39 |
| ▸ | GCK | P35557 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 3/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | CHKA | P35790 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1097561 | 0.80 | CHKA (0.52) | HRH4MEN1KMT2AGAALMNA | |
| SCHEMBL16212228 | 0.80 | HRH4 (0.47) | HRH4MEN1KMT2AGLAGAA | |
| SCHEMBL10771091 | 0.80 | HRH4 (0.42) | HRH4MEN1KMT2AGLAGAA | |
| SCHEMBL30321663 | 0.79 | LGMN (0.53) | CDK2LMNAMAPTSMN1; SMN2CDK1 | |
| SCHEMBL3173446 | 0.79 | GAA (0.60) | HRH4MEN1KMT2AGLAGAA | |
| SCHEMBL114416 | 0.79 | LGMN (0.53) | CDK2LMNAMAPTSMN1; SMN2CDK1 | |
| SCHEMBL6262576 | 0.79 | HRH4 (0.54) | HRH4MEN1KMT2AGAALMNA | |
| SCHEMBL5847761 | 0.79 | HRH4 (0.54) | HRH4MEN1KMT2AGAALMNA | |
| SCHEMBL20557381 | 0.79 | CDC7 (0.42) | HRH4GCKMEN1KMT2AGLA | |
| SCHEMBL21590373 | 0.78 | HRH3 (0.53) | HRH4MEN1KMT2ACDK2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0244115-A2 | Phenyl-piperazine anti-arrhythmia agents | Pfizer Limited (GB) | 1987-11-04 | — | — | EP | disclosed |