Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | CHKA | P35790 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | PRDM9 | Q9NQV7 | 1/20 | 0.36 |
| ▸ | PRDM7 | Q9NQW5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21186191 | 0.88 | HRH4 (0.50) | HRH4AOC3LDHAUHRF1MEN1 | |
| Water SCHEMBL28114608 | 0.82 | HRH4 (0.54) | HRH4LDHAUHRF1MEN1KMT2A | |
| SCHEMBL13027974 | 0.81 | HRH4 (0.61) | HRH4MEN1KMT2AGLAGAA | |
| SCHEMBL425041 | 0.80 | HRH4 (0.56) | HRH4LDHAUHRF1MEN1KMT2A | |
| SCHEMBL10682305 | 0.80 | MAPT (0.53) | HRH4AOC3MEN1KMT2AGLA | |
| SCHEMBL10767289 | 0.80 | HRH4 (0.39) | HRH4MEN1KMT2AGLAGAA | |
| SCHEMBL11981573 | 0.79 | TP53 (0.49) | MEN1KMT2APSEN1PSEN2APH1B | |
| SCHEMBL7010820 | 0.79 | HRH4 (0.44) | HRH4AOC3LDHAUHRF1MEN1 | |
| SCHEMBL9455784 | 0.79 | HRH4 (0.58) | HRH4UHRF1MEN1KMT2AGLA | |
| SCHEMBL24767206 | 0.78 | LDHA (0.45) | HRH4LDHAUHRF1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0244115-A2 | Phenyl-piperazine anti-arrhythmia agents | Pfizer Limited (GB) | 1987-11-04 | — | — | EP | disclosed |