Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9116157 | 0.76 | KDM4E (0.34) | ALDH1A1 | |
| SCHEMBL10766473 | 0.75 | S1PR1 (0.39) | CLK4TNFALDH1A1S1PR1GLA | |
| SCHEMBL16955156 | 0.74 | ENPP2 (0.40) | CLK4TNFS1PR1GLAENPP2 | |
| SCHEMBL6163795 | 0.71 | ENPP2 (0.46) | CLK4TNFALDH1A1S1PR1ENPP2 | |
| SCHEMBL7868571 | 0.71 | ADRA1D (0.36) | CLK4ALDH1A1S1PR1GLAENPP2 | |
| SCHEMBL5313501 | 0.71 | UGT2B7 (0.43) | — | |
| SCHEMBL24527555 | 0.69 | ALDH1A1 (0.40) | TNFALDH1A1S1PR1GLAKCNA5 | |
| SCHEMBL16959032 | 0.69 | GLA (0.44) | CLK4S1PR1CREBBPGLAENPP2 | |
| SCHEMBL104898 | 0.68 | GLA (0.46) | CLK4ALDH1A1S1PR1CREBBPGLA | |
| SCHEMBL4083138 | 0.67 | ENPP2 (0.47) | CLK4TNFALDH1A1S1PR1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0235452-A2 | Organic compounds and their pharmaceutical use | LILLY INDUSTRIES LIMITED (GB) | 1987-09-09 | — | — | EP | disclosed |