Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.39 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10772284 | 0.86 | ALDH1A1 (0.43) | TNKSPARP1TNKS2NPC1RAB9A | |
| SCHEMBL1423662 | 0.81 | TNKS (0.56) | TNKSPARP1TNKS2NPC1GAA | |
| SCHEMBL10770165 | 0.75 | ALDH1A1 (0.57) | TNKSPARP1TNKS2KDM4CADORA3 | |
| SCHEMBL15775394 | 0.74 | TNKS (0.68) | TNKSPARP1TNKS2NPC1GAA | |
| SCHEMBL25696459 | 0.73 | MAPK1 (0.48) | TNKSPARP1TNKS2NPC1GAA | |
| SCHEMBL2744822 | 0.73 | NPC1 (0.61) | TNKSPARP1TNKS2NPC1GAA | |
| SCHEMBL10768282 | 0.71 | TNKS (0.58) | TNKSPARP1TNKS2NPC1RAB9A | |
| SCHEMBL10771264 | 0.71 | TNKS (0.58) | TNKSPARP1TNKS2NPC1GAA | |
| SCHEMBL10771178 | 0.71 | TNKS (0.58) | TNKSPARP1TNKS2NPC1RAB9A | |
| SCHEMBL280520 | 0.68 | TNKS (0.54) | TNKSPARP1TNKS2NPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0223420-A1 | Condensed imidazopyridine derivatives | SHIONOGI & CO., LTD. (JP) | 1987-05-27 | — | — | EP | disclosed |