Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.86 |
| ▸ | EGFR | P00533 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10768964 | 0.82 | KMT2A (0.64) | KMT2AEGFRALDH1A1ALOX12MAPT | |
| SCHEMBL5455537 | 0.80 | ALDH1A1 (0.69) | KMT2AEGFRALDH1A1HTTMAPT | |
| SCHEMBL11135607 | 0.76 | ALDH1A1 (0.57) | KMT2AALDH1A1HTTMAPTMAPK1 | |
| SCHEMBL11137929 | 0.76 | KMT2A (0.64) | KMT2AEGFRALDH1A1HTTALOX12 | |
| SCHEMBL10887028 | 0.74 | KDM4E (0.56) | KMT2AALDH1A1MAPK1MEN1 | |
| SCHEMBL10888698 | 0.74 | KDM4E (0.56) | KMT2AALDH1A1MAPK1MEN1 | |
| SCHEMBL10891925 | 0.74 | KDM4E (0.56) | KMT2AALDH1A1MAPK1MEN1 | |
| SCHEMBL10891067 | 0.74 | KDM4E (0.56) | KMT2AALDH1A1MAPK1MEN1 | |
| SCHEMBL10886838 | 0.74 | KDM4E (0.56) | KMT2AALDH1A1MAPK1MEN1 | |
| SCHEMBL10887592 | 0.74 | KDM4E (0.56) | KMT2AALDH1A1MAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239170-A1 | Stabilized lactam polymerization solutions | DSM RIM NYLON V.O.F (NL) | 1987-09-30 | — | — | EP | disclosed |
| US-4694039-A | Stabilized lactam polymerization solutions | DSM RIM NYLON V.O.F. (NL) | 1987-09-15 | — | — | US | disclosed |
| US-4672085-A | LACTAM SUBSTITUTED POLYBUTADIENE INITIATOR,TRISUBTITED UREA STABILIZER;NYLON BLOCK COPOLYMERS | DSM RIM NYLON VOF (NL) | 1987-06-09 | — | — | US | disclosed |