SCHEMBL5455537

SCHEMBL5455537

CCCCN(Cc1ccccc1)C(=S)Nc1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.69
EGFR P00533 5/20 0.67
ERBB2 P04626 3/20 0.65
LMNA P02545 7/20 0.64
MAPK1 P28482 1/20 0.60
SMN1; SMN2 Q16637 4/20 0.60
MAPT P10636 2/20 0.60
GAA P10253 2/20 0.59
MEN1 O00255 1/20 0.57
KMT2A Q03164 1/20 0.57
HTT P42858 1/20 0.57
KDM4E B2RXH2 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5449574 0.91 EGFR (0.68) ALDH1A1EGFRERBB2LMNAMAPK1
SCHEMBL5455476 0.84 MAPK1 (0.81) ALDH1A1EGFRERBB2LMNAMAPK1
SCHEMBL17956765 0.84 EGFR (0.61) ALDH1A1EGFRERBB2LMNAMAPK1
SCHEMBL5463525 0.84 LMNA (0.81) ALDH1A1EGFRERBB2LMNAMAPK1
SCHEMBL11141720 0.82 HDAC6 (0.77) ALDH1A1EGFRLMNASMN1; SMN2KDM4E
SCHEMBL5464300 0.81 ALDH1A1 (0.66) ALDH1A1EGFRERBB2LMNAMAPK1
SCHEMBL10768960 0.80 KMT2A (0.86) ALDH1A1EGFRERBB2LMNAMAPK1
SCHEMBL10768964 0.79 KMT2A (0.64) ALDH1A1EGFRERBB2LMNAMAPK1
SCHEMBL8829693 0.79 EGFR (0.58) ALDH1A1EGFRERBB2LMNAMAPK1
SCHEMBL5320176 0.78 GRIN2D (0.55) ALDH1A1LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101129295-B There is the binary initiator system of good storage stability and especially suitable for acidic system HERAEUS KULZER GMBH (DE) 2016-02-10 CN disclosed
CN-101129295-A 2-component initiator system (amine free) with storage stability and especially suitable for acidic systems HERAEUS KULZER GMBH (DE) 2008-02-27 CN disclosed
US-20070040151-A1 Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems HERAEUS KULZER GMBH (DE) 2007-02-22 US disclosed