SCHEMBL107695

SCHEMBL107695

C=CC(=O)OC(CC)CC(C)(C)O[SiH3]

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.33
HPGD P15428 1/20 0.33
THRB P10828 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28170374 0.83 THRB (0.33) TSHRHPGDTHRB
SCHEMBL28118439 0.81 TSHR (0.32) TSHRHPGD
SCHEMBL3760078 0.80 TSHR (0.35) TSHRHPGDTHRB
SCHEMBL3344615 0.80 MEN1 (0.33) TSHR
SCHEMBL11143548 0.79 TSHR (0.39) TSHRHPGDTHRB
SCHEMBL561301 0.78 TSHR (0.45) TSHRHPGDTHRB
SCHEMBL13562098 0.77 ALDH1A1 (0.36) TSHRHPGDTHRB
SCHEMBL25276753 0.77
SCHEMBL4394881 0.76 TSHR (0.41) TSHRHPGDTHRB
SCHEMBL109234 0.75 TSHR (0.36) TSHRHPGDTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025045754-A1 POLYAMIDE MOULDING COMPOUND FOR PRODUCING COMPONENTS WITH A HIGH WELD LINE STRENGTH EMS-CHEMIE AG (CH) 2025-03-06 WO disclosed
US-20240409563-A1 HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME GELEST, INC. 2024-12-12 US disclosed
EP-4448536-A1 HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME GELEST, INC. (US) 2024-10-23 EP disclosed
US-12097497-B2 Cell accommodating chip YAMATO SCIENTIFIC CO., LTD. (JP) 2024-09-24 US disclosed
US-20240279459-A1 Curable Composition and Cured Product SOKEN CHEMICAL & ENGINEERING CO., LTD. (JP) 2024-08-22 US disclosed
US-20240279441-A1 RUBBER COMPOSITION AND TIRE BRIDGESTONE CORPORATION (JP) 2024-08-22 US disclosed
EP-3507011-B1 SHAPED GEL ARTICLES AND SINTERED ARTICLES PREPARED THEREFROM 3M INNOVATIVE PROPERTIES COMPANY (US) 2024-06-26 EP disclosed
EP-4353755-A1 CURABLE COMPOSITION AND CURED PRODUCT Soken Chemical & Engineering Co., Ltd. (JP) 2024-04-17 EP disclosed
EP-4349902-A1 RUBBER COMPOSITION AND TIRE BRIDGESTONE CORPORATION (JP) 2024-04-10 EP disclosed
US-20240043340-A1 HAPTIC ARTICLES AND APPLICATIONS USING SINTERED ARTICLES PREPARED FROM MOLDED GEL COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY 2024-02-08 US disclosed
US-20060100405-A1 Copolymer having reactive silicon-containing group and organic-inorganic hybrid polymeric material ARAKAWA MOTOOMI 2006-05-11 US disclosed
EP-1645560-A1 Monofunctional monomer having cage oligosiloxane structure and method of making Shin-Etsu Chemical Co., Ltd. (JP) 2006-04-12 EP disclosed
US-20060074213-A1 Monofunctional monomer having cage oligosiloxane structure and method of making SHIN-ETSU CHEMICAL CO., LTD. (JP) 2006-04-06 US disclosed
US-20040127663-A1 Copolymer having reactive silicon-containing group and organic-inorganic hybrid polymeric material ORIENT CHEMICAL INDUSTRIES, LTD. (JP) 2004-07-01 US disclosed
EP-1433798-A1 Copolymer having reactive silicon-containing group and organic-inorganic hybrid polymeric material Orient Chemical Industries, Ltd. (JP) 2004-06-30 EP disclosed
US-6136926-A CURING WITH ETHYLENICALLY UNSATURATED ORGANOSILANE COMPOUND; HEATING BELOW SOFTENING POINT BOREALIS GMBH (AT) 2000-10-24 US disclosed
EP-0695783-B1 Low solvent content type-resin composition, coating composition containing such resin composition and process for coating such coating composition MAZDA MOTOR (JP) 2000-02-02 EP disclosed
US-5650475-A VINYL POLYMERS WITH BLOCKED CARBOXY, SILANOL, EPOXY, HYDROLYZED SILYL AND ACID ANHYDRIDES IN SOLVENTS MAZDA MOTOR CORPORATION (JP) 1997-07-22 US disclosed
EP-0695783-A2 Low solvent content type-resin composition, coating composition containing such resin composition and process for coating such coating composition Mazda Motor Corporation (JP) 1996-02-07 EP disclosed
EP-0688841-A2 Low solvent content type-resin composition, coating composition containing such resin composition and process for coating such coating composition MAZDA MOTOR CORPORATION (JP) 1995-12-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240409563-A1 HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME SSRP1, RPLP2, RPLP1 TSHR 1897/4885HPGD 3909/4885THRB 2939/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.