SCHEMBL107697

SCHEMBL107697

NCCOC(=O)[C@@H](N)CS

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.46
SLC7A11 Q9UPY5 1/20 0.46
CTH P32929 1/20 0.34
CPB2 Q96IY4 3/20 0.34
LMNA P02545 1/20 0.33
ENPEP Q07075 4/20 0.32
ANPEP P15144 2/20 0.31
GSR P00390 1/20 0.31
IDO1 P14902 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5150211 0.87 PTGS1 (0.43) PTGS1SLC7A11CPB2ENPEPGSR
SCHEMBL6039402 0.87 PTGS1 (0.43) PTGS1SLC7A11CPB2ENPEPGSR
SCHEMBL6891065 0.84 PTGS1 (0.48) PTGS1SLC7A11ENPEPANPEP
SCHEMBL22331154 0.82 PTGS1 (0.46) PTGS1SLC7A11ENPEPANPEP
SCHEMBL2675600 0.82 PTGS1 (0.46) PTGS1SLC7A11ENPEPANPEP
SCHEMBL22331155 0.82 PTGS1 (0.46) PTGS1SLC7A11ENPEPANPEP
SCHEMBL28065154 0.81
Hydrochloric Acid SCHEMBL9123179 0.81 ANPEP (0.35) PTGS1SLC7A11CTHCPB2LMNA
SCHEMBL111370 0.80 PTGS1 (0.44) PTGS1SLC7A11CPB2LMNAENPEP
Hydrochloric Acid SCHEMBL22331153 0.80 PTGS1 (0.44) PTGS1SLC7A11ENPEPANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 632 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11084836-B2 Compositions useful in therapy of autophagy-related pathologies, and methods of making and using the same THE UNIVERSITY OF TOLEDO (US) 2021-08-10 US claimed
US-20190270786-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 AND THEIR USE TO TREAT INFLAMMATORY DISEASES PROTAGONIST THERAPEUTICS, INC. 2019-09-05 US claimed
WO-2018022937-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 AND THEIR USE TO TREAT INFLAMMATORY DISEASES PROTAGONIST THERAPEUTICS, INC. (US) 2018-02-01 WO claimed
CN-106442758-A Liquid mass spectrometry method for detecting various amino acids in human blood plasma in underivatized mode 陈大为 2017-02-22 CN claimed
EP-1750126-B1 METHOD AND APPARATUS FOR ANALYZING AMINOFUNCTIONAL COMPOUND AJINOMOTO KK (JP) 2015-09-16 EP claimed
US-20130291138-A1 METHOD TO ENHANCE YIELD AND PURITY OF HYBRID CROPS MONSANTO TECHNOLOGY LLC (US) 2013-10-31 US claimed
US-20130074213-A1 METHODS FOR PRODUCING HYBRID SEED MONSANTO TECHNOLOGY LLC (US) 2013-03-21 US claimed
CN-101631566-A Polar hydrophilic prodrugs of amphetamine and other stimulants and processes for making and using the same KEMPHARM INC 2010-01-20 CN claimed
EP-2109465-A2 POLAR HYDROPHILIC PRODRUGS OF AMPHETAMINE AND OTHER STIMULANTS AND PROCESSES FOR MAKING AND USING THE SAME Kempharm, Inc. (US) 2009-10-21 EP claimed
US-20090239949-A1 Polar Hydrophilic Prodrugs of Amphetamine and Other Stimulants and Processes for Making and Using the Same SHIRE LLC 2009-09-24 US claimed
WO-2008098151-A2 POLAR HYDROPHILIC PRODRUGS OF AMPHETAMINE AND OTHER STIMULANTS AND PROCESSES FOR MAKING AND USING THE SAME KEMPHARM, INC. (US) 2008-08-14 WO claimed
EP-1934354-A2 METHODS FOR PRODUCING HYBRID SEED Mosanto Technology, LLC (US) 2008-06-25 EP claimed
US-20070269899-A1 METHOD AND APPARATUS FOR ANALYZING COMPOUNDS WITH AMINO GROUP AJINOMOTO CO. INC. (JP) 2007-11-22 US claimed
US-20070199095-A1 Methods for producing hybrid seed MONSANTO TECHNOLOGY LLC 2007-08-23 US claimed
WO-2007047016-A2 METHODS FOR PRODUCING HYBRID SEED MONSANTO TECHNOLOGY, LLC (US) 2007-04-26 WO claimed
EP-1750126-A1 METHOD AND APPARATUS FOR ANALYZING AMINOFUNCTIONAL COMPOUND Ajinomoto Co., Inc. (JP) 2007-02-07 EP claimed
US-5316930-A DNA molecules and plant or bacteria cells PIONEER HI-BRED INTERNATIONAL, INC. (US) 1994-05-31 US claimed
EP-0240332-A2 Virus resistant plants having antisense RNA PIONEER HI-BRED INTERNATIONAL, INC. (US) 1987-10-07 EP claimed
EP-0240331-A2 Virus resistant plants having a viral coat protein PIONEER HI-BRED INTERNATIONAL, INC. (US) 1987-10-07 EP claimed
EP-0140556-A1 A T-DNA derived vector LUBRIZOL GENETICS INC. (US) 1985-05-08 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090239949-A1 Polar Hydrophilic Prodrugs of Amphetamine and Other Stimulants and Processes for Making and Using the Same SLC6A2, SLC6A3, SLC18A2 PTGS1 3470/4885SLC7A11 1102/4885CTH 3633/4885
US-20190270786-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 AND THEIR USE TO TREAT INFLAMMATORY DISEASES IL23R, IL17A, VIP PTGS1 1359/4885SLC7A11 2141/4885CTH 1056/4885
US-11084836-B2 Compositions useful in therapy of autophagy-related pathologies, and methods of making and using the same TFEB, SQSTM1, BECN1 PTGS1 2945/4885SLC7A11 377/4885CTH 319/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.