Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.42 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9501954 | 0.83 | KCNH2 (0.58) | KCNH2HRH3KDM4EALDH1A1POLB | |
| SCHEMBL9504545 | 0.81 | KCNH2 (0.63) | KCNH2HRH3KDM4EALDH1A1POLB | |
| SCHEMBL9873805 | 0.77 | CACNA1F (0.69) | KCNH2KDM4EALDH1A1POLBCACNA1F | |
| SCHEMBL10813681 | 0.76 | KDM4E (0.74) | KDM4EALDH1A1HPGDLMNAHSD17B10 | |
| SCHEMBL9503714 | 0.73 | KCNH2 (0.51) | KCNH2HRH3KDM4EALDH1A1POLB | |
| SCHEMBL10570462 | 0.70 | KCNH2 (0.67) | KCNH2HRH3KDM4EALDH1A1POLB | |
| SCHEMBL8325557 | 0.70 | CHRM2 (0.49) | KCNH2HRH3KDM4EALDH1A1POLB | |
| SCHEMBL8325559 | 0.70 | CHRM2 (0.49) | KCNH2HRH3KDM4EALDH1A1POLB | |
| SCHEMBL30564254 | 0.69 | KDM4E (0.81) | KCNH2KDM4EALDH1A1POLBHPGD | |
| SCHEMBL8199125 | 0.68 | KCNH2 (0.74) | KCNH2HRH3KDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0221463-A2 | Quinoline derivatives and processes for preparation thereof | Dainippon Pharmaceutical Co., Ltd. (JP) | 1987-05-13 | — | — | EP | disclosed |