Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.48 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10421314 | 1.00 | HTR2A (0.54) | HTR2ALMNASIGMAR1GRIK1GRIK2 | |
| SCHEMBL3524487 | 0.86 | SIGMAR1 (0.51) | HTR2ALMNASIGMAR1GRIK1GRIK2 | |
| SCHEMBL10769885 | 0.77 | SIGMAR1 (0.53) | HTR2ALMNASIGMAR1GRIK1GRIK2 | |
| SCHEMBL10421315 | 0.77 | CYP1A2 (0.48) | HTR2ALMNASIGMAR1GRIK1GRIK2 | |
| SCHEMBL402415 | 0.75 | TAAR1 (0.69) | LMNAKMT2ATAAR1CYP2C19FFAR1 | |
| SCHEMBL10421320 | 0.75 | LMNA (0.42) | HTR2ALMNASIGMAR1KMT2AFFAR1 | |
| SCHEMBL24814159 | 0.74 | GRIK1 (0.56) | HTR2ALMNAGRIK1GRIK2KMT2A | |
| SCHEMBL29178391 | 0.74 | GRIK1 (0.56) | HTR2ALMNAGRIK1GRIK2KMT2A | |
| SCHEMBL1790978 | 0.74 | KMT2A (0.63) | KMT2AHDAC1HDAC2HDAC8CYP3A4 | |
| SCHEMBL2236118 | 0.74 | KMT2A (0.63) | KMT2AHDAC1HDAC2HDAC8CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215297-A2 | Substituted dipeptide amides | G.D. Searle & Co. (US) | 1987-03-25 | — | — | EP | disclosed |