Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9650477 | 0.86 | LMNA (0.35) | LMNAADRB2ADRB1HTR1ASLC6A2 | |
| SCHEMBL9648721 | 0.84 | LMNA (0.35) | LMNAADRB2ADRB1HTR1ASLC6A2 | |
| SCHEMBL9649347 | 0.70 | LMNA (0.38) | LMNATSHRPOLBKDM4ECYP3A4 | |
| SCHEMBL10360151 | 0.69 | ALDH1A1 (0.37) | LMNAADRB2ADRB1TSHRPOLB | |
| SCHEMBL9650500 | 0.69 | LMNA (0.39) | LMNAADRB2ADRB1HTR1ASLC6A2 | |
| SCHEMBL9446788 | 0.69 | — | — | |
| SCHEMBL9648708 | 0.68 | LMNA (0.39) | LMNAADRB2ADRB1HTR1ASLC6A2 | |
| SCHEMBL9646502 | 0.66 | LMNA (0.31) | LMNAADRB2ADRB1HTR1ASLC6A2 | |
| SCHEMBL9649444 | 0.64 | USP8 (0.31) | — | |
| SCHEMBL9648996 | 0.63 | USP8 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0244728-A2 | Use of heteroarylethyl amines to stimulate animal growth, heteroarylethyl amines and process for their preparation | BAYER AG (DE) | 1987-11-11 | — | — | EP | disclosed |