Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.33 |
| ▸ | GLS | O94925 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9648823 | 0.79 | S1PR2 (0.39) | MAPK1S1PR2ALDH1A1CYP3A4HTT | |
| SCHEMBL9446749 | 0.79 | ALDH1A1 (0.40) | LMNAMAPK1TSHRS1PR2GLS | |
| SCHEMBL9650500 | 0.77 | LMNA (0.39) | LMNAMAPK1TSHRALDH1A1CYP3A4 | |
| SCHEMBL10691888 | 0.76 | ALDH1A1 (0.57) | TSHRUSP2GLSSMN1; SMN2ALDH1A1 | |
| SCHEMBL9650477 | 0.75 | LMNA (0.35) | LMNAMAPK1TSHRCYP3A4KDM4E | |
| SCHEMBL27951542 | 0.75 | S1PR2 (0.36) | S1PR2ALDH1A1HTTKDM4ESCN9A | |
| SCHEMBL10770096 | 0.70 | LMNA (0.31) | LMNATSHRCYP3A4KDM4EPOLB | |
| SCHEMBL10489095 | 0.68 | ALDH1A1 (0.46) | MAPK1SMN1; SMN2ALDH1A1CYP3A4POLB | |
| SCHEMBL15418992 | 0.68 | ACACB (0.35) | SCN9A | |
| SCHEMBL1368673 | 0.67 | S1PR2 (0.40) | LMNAS1PR2ALDH1A1HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0244728-B1 | USE OF HETEROARYLETHYL AMINES TO STIMULATE ANIMAL GROWTH, HETEROARYLETHYL AMINES AND PROCESS FOR THEIR PREPARATION | BAYER AG (DE) | 1992-11-11 | — | — | EP | disclosed |
| EP-0244728-A2 | Use of heteroarylethyl amines to stimulate animal growth, heteroarylethyl amines and process for their preparation | BAYER AG (DE) | 1987-11-11 | — | — | EP | disclosed |