Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | CBFB | Q13951 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.49 |
| ▸ | SCD | O00767 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10770346 | 0.90 | RAB9A (0.61) | HDAC6KDM4ENPC1ALDH1A1TP53 | |
| Water SCHEMBL10770066 | 0.84 | HDAC6 (0.68) | HDAC6CBFBCYP2C9CYP2C19CYP1A2 | |
| SCHEMBL4360279 | 0.84 | HDAC6 (0.76) | HDAC6KDM4ENPC1ALDH1A1TP53 | |
| SCHEMBL5178280 | 0.80 | HDAC6 (0.84) | HDAC6KDM4ENPC1ALDH1A1HPGD | |
| Ensulizole SCHEMBL7751558 | 0.80 | HDAC6 (1.00) | HDAC6KDM4ENPC1ALDH1A1TP53 | |
| Ensulizole SCHEMBL38724 | 0.80 | HDAC6 (1.00) | HDAC6KDM4ENPC1ALDH1A1TP53 | |
| Ensulizole SCHEMBL28708898 | 0.79 | HDAC6 (0.97) | HDAC6KDM4ENPC1ALDH1A1TP53 | |
| Ensulizole SCHEMBL1276071 | 0.79 | HDAC6 (0.97) | HDAC6KDM4ENPC1ALDH1A1TP53 | |
| Ensulizole SCHEMBL17351654 | 0.79 | HDAC6 (0.97) | HDAC6KDM4ENPC1ALDH1A1TP53 | |
| SCHEMBL490323 | 0.78 | HDAC6 (0.86) | HDAC6CYP2C9CYP2C19CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0218753-A1 | Image-recieving element for the silver salt diffusion transfer reversal process | AGFA-GEVAERT N.V. (BE) | 1987-04-22 | — | — | EP | disclosed |