Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.86 |
| ▸ | SCD | O00767 | 8/20 | 0.66 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.62 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15895542 | 0.93 | HDAC6 (0.75) | HDAC6SCDNPBWR1CHEK2CYP2C9 | |
| SCHEMBL5178280 | 0.93 | HDAC6 (0.84) | HDAC6SCDNPBWR1CHEK2CYP2C9 | |
| SCHEMBL30884657 | 0.93 | HDAC6 (0.94) | HDAC6SCDNPBWR1CHEK2CYP2C9 | |
| Ensulizole SCHEMBL38724 | 0.92 | HDAC6 (1.00) | HDAC6SCDNPBWR1CHEK2CYP2C9 | |
| Ensulizole SCHEMBL7751558 | 0.92 | HDAC6 (1.00) | HDAC6SCDNPBWR1CHEK2CYP2C9 | |
| Ensulizole SCHEMBL1276071 | 0.91 | HDAC6 (0.97) | HDAC6SCDNPBWR1CHEK2CYP2C9 | |
| Ensulizole SCHEMBL28708898 | 0.91 | HDAC6 (0.97) | HDAC6SCDNPBWR1CHEK2CYP2C9 | |
| Ensulizole SCHEMBL17351654 | 0.91 | HDAC6 (0.97) | HDAC6SCDNPBWR1CHEK2CYP2C9 | |
| SCHEMBL5686285 | 0.90 | HDAC6 (0.76) | HDAC6SCDNPBWR1CHEK2 | |
| Water SCHEMBL10770159 | 0.90 | HDAC6 (0.75) | HDAC6SCDNPBWR1CHEK2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210346249-A1 | COMPOSITION COMPRISING A UV-SCREENING AGENT, AN ANIONIC CROSSLINKED HYDROPHILIC POLYMER, A SURFACTANT HAVING AN HLB LESS THAN OR EQUAL TO 5 AND A SILICONE COPOLYMER | L'OREAL (FR) | 2021-11-11 | — | — | US | disclosed |
| EP-3185843-B1 | GEL COMPOSITION AND GEL COMPRISING A UV FILTER | OREAL (FR) | 2021-08-11 | — | — | EP | disclosed |
| EP-3389618-B1 | PROCESS FOR TREATING KERATIN FIBRES USING AN AQUEOUS COMPOSITION COMPRISING A COMBINATION OF PARTICULAR ALKOXYSILANES | OREAL (FR) | 2021-01-20 | — | — | EP | disclosed |
| EP-3389604-B1 | COMPOSITION COMPRISING A COMBINATION OF PARTICULAR ALKOXYSILANES AND A FATTY SUBSTANCE | OREAL (FR) | 2020-04-08 | — | — | EP | disclosed |
| US-20200030200-A1 | COMPOSITION COMPRISING A UV-SCREENING AGENT, AN ANIONIC CROSSLINKED HYDROPHILIC POLYMER, A SURFACTANT HAVING AN HLB LESS THAN OR EQUAL TO 5 AND A SILICONE COPOLYMER | L'OREAL (FR) | 2020-01-30 | — | — | US | disclosed |
| EP-3307233-B1 | COMPOSITION COMPRISING A UV-SCREENING AGENT, AN ANIONIC CROSSLINKED HYDROPHILIC POLYMER, A SURFACTANT HAVING AN HLB LESS THAN OR EQUAL TO 5 AND A SILICONE COPOLYMER | OREAL (FR) | 2019-11-06 | — | — | EP | disclosed |
| EP-2259768-B1 | COMPOSITIONS CONTAINING CYCLIC PEPTIDES AND METHODS OF USE | MERCK PATENT GMBH (DE) | 2019-05-22 | — | — | EP | disclosed |
| US-10278911-B2 | Compositions containing cyclic peptides and methods of use | MERCK PATENT GMBH (DE) | 2019-05-07 | — | — | US | disclosed |
| EP-2945603-B1 | COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND A UVA-SCREENING AGENT OF THE AMINO-SUBSTITUTED 2-HYDROXYBENZOPHENONE TYPE AND/OR A HYDROPHILIC ORGANIC UVA-SCREENING AGENT | OREAL (FR) | 2019-03-27 | — | — | EP | disclosed |
| WO-2019002494-A1 | USE OF A WASHING COMPOSITION COMPRISING SURFACTANTS AND CATIONIC AND/OR AMPHOTERIC POLYMERS IN COMBINATION WITH A COMPOSITION COMPRISING ANIONIC BENEFICIAL AGENTS | L'OREAL (FR) | 2019-01-03 | — | — | WO | disclosed |
| US-20050043398-A1 | Use of chromen-4-one derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2005-02-24 | — | — | US | disclosed |
| EP-1508327-A1 | Use of chromen-4-one derivatives for the care of skin and hair | MERCK PATENT GmbH (DE) | 2005-02-23 | — | — | EP | disclosed |
| US-20050019426-A1 | For care, protection from aging of skin and hair, use in treatment of various skin disorders such as leukoplakia, eczema, keratosis, psoriasis, or to promote wound healing | MERCK PATENT GMBH (DE) | 2005-01-27 | — | — | US | disclosed |
| EP-1493431-A2 | Use of an extract of bauhinia for the preparation of pharmaceutical and cosmetic compositions | MERCK PATENT GmbH (DE) | 2005-01-05 | — | — | EP | disclosed |
| WO-2004092283-A2 | ANTIMICROBIAL PIGMENTS | MERCK PATENT GMBH (DE) | 2004-10-28 | — | — | WO | disclosed |
| WO-2004091567-A2 | COSMETIC FORMULATIONS COMPRISING ANTIMICROBIAL PIGMENTS | MERCK PATENT GMBH (DE) | 2004-10-28 | — | — | WO | disclosed |
| US-20040091433-A1 | Light-protection agents | MERCK PATENT GMBH (DE) | 2004-05-13 | — | — | US | disclosed |
| US-20040067894-A1 | Preparation having antioxidant properties | MERCK PATENT GMBH (DE) | 2004-04-08 | — | — | US | disclosed |
| EP-1400579-A2 | Composition with anti-oxidative properties | MERCK PATENT GmbH (DE) | 2004-03-24 | — | — | EP | disclosed |
| EP-1382329-A1 | Compositions for photoprotection comprising a flavonoid | MERCK PATENT GmbH (DE) | 2004-01-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040091433-A1 | Light-protection agents | CBR1, CYC1, C9 | HDAC6 3965/4885SCD 1780/4885NPBWR1 957/4885 |
| US-20040067894-A1 | Preparation having antioxidant properties | GPX1, CBR1, CYC1 | HDAC6 2984/4885SCD 1009/4885NPBWR1 1936/4885 |
| US-10278911-B2 | Compositions containing cyclic peptides and methods of use | CUTA, NGLY1, CALCA | HDAC6 2640/4885SCD 3637/4885NPBWR1 160/4885 |
| US-20200030200-A1 | COMPOSITION COMPRISING A UV-SCREENING AGENT, AN ANIONIC CROSSLINKED HYDROPHILIC POLYMER, A SURFACTANT HAVING AN HLB LESS THAN OR EQUAL TO 5 AND A SILICONE COPOLYMER | ERCC5, CUTA, PLIN5 | HDAC6 4356/4885SCD 1595/4885NPBWR1 2990/4885 |
| US-20050019426-A1 | For care, protection from aging of skin and hair, use in treatment of various skin disorders such as leukoplakia, eczema, keratosis, psoriasis, or to promote wound healing | ITCH, CUTA, POLR1C | HDAC6 2009/4885SCD 2886/4885NPBWR1 4391/4885 |
| US-20050043398-A1 | Use of chromen-4-one derivatives | CYP8B1, CYP7B1, CYP2R1 | HDAC6 2592/4885SCD 2562/4885NPBWR1 3840/4885 |
| US-20210346249-A1 | COMPOSITION COMPRISING A UV-SCREENING AGENT, AN ANIONIC CROSSLINKED HYDROPHILIC POLYMER, A SURFACTANT HAVING AN HLB LESS THAN OR EQUAL TO 5 AND A SILICONE COPOLYMER | ERCC5, CUTA, PLIN5 | HDAC6 4356/4885SCD 1595/4885NPBWR1 2990/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.