Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 19/20 | 0.69 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL10773835 | 0.85 | REN (0.63) | RENPSMB5 | |
| Fluoride SCHEMBL10774287 | 0.83 | REN (0.60) | RENPSMB5 | |
| SCHEMBL10772032 | 0.79 | REN (0.64) | RENPSMB5 | |
| SCHEMBL7269511 | 0.78 | REN (0.82) | REN | |
| SCHEMBL7268300 | 0.78 | REN (0.82) | REN | |
| SCHEMBL7268305 | 0.78 | REN (0.82) | REN | |
| SCHEMBL7270080 | 0.77 | REN (0.80) | REN | |
| SCHEMBL7270226 | 0.77 | REN (0.80) | REN | |
| SCHEMBL7270076 | 0.77 | REN (0.80) | REN | |
| SCHEMBL7269257 | 0.75 | REN (0.76) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0228192-A2 | Renin-inhibitory oligopeptides, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1987-07-08 | — | — | EP | disclosed |