Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 4/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.34 |
| ▸ | PDE8B | O95263 | 4/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31178734 | 0.83 | ATR (0.39) | CYP4F2CYP4A11RXRARXRBRXRG | |
| SCHEMBL806435 | 0.77 | USP2 (0.49) | HCAR3ALDH1A1USP2LMNAPOLB | |
| SCHEMBL10775612 | 0.76 | ALDH1A1 (0.39) | CYP4F2CYP4A11GRM2PDE8BALDH1A1 | |
| SCHEMBL10770970 | 0.76 | ALDH1A1 (0.39) | CYP4F2CYP4A11GRM2PDE8BALDH1A1 | |
| SCHEMBL10775607 | 0.76 | ALDH1A1 (0.39) | CYP4F2CYP4A11GRM2PDE8BALDH1A1 | |
| SCHEMBL10770782 | 0.76 | ALDH1A1 (0.39) | CYP4F2CYP4A11GRM2PDE8BALDH1A1 | |
| SCHEMBL10770777 | 0.76 | ALDH1A1 (0.39) | CYP4F2CYP4A11GRM2PDE8BALDH1A1 | |
| SCHEMBL31178745 | 0.76 | VCP (0.32) | CYP4F2CYP4A11RXRARXRBRXRG | |
| SCHEMBL1141884 | 0.76 | RXRA (0.45) | CYP4F2CYP4A11RXRARXRBRXRG | |
| SCHEMBL31190729 | 0.74 | CYP4F2 (0.37) | CYP4F2CYP4A11RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0231444-A2 | Optically active isomers and racemate of 1-(benztriazol-4-yloxy)-3-[2-(2-methoxyphenoxy)-ethylamino]-2-propanol, process for their preparation as well as their use as medicaments | Roche Diagnostics GmbH (DE) | 1987-08-12 | — | — | EP | claimed |
| EP-0231444-A2 | Optically active isomers and racemate of 1-(benztriazol-4-yloxy)-3-[2-(2-methoxyphenoxy)-ethylamino]-2-propanol, process for their preparation as well as their use as medicaments | Roche Diagnostics GmbH (DE) | 1987-08-12 | — | — | EP | disclosed |