Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL117142 | 0.89 | HTT (0.46) | HTTPOLBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9720183 | 0.86 | HTT (0.42) | HTTPOLBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL393744 | 0.79 | HTT (0.43) | HTTPOLBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL1334752 | 0.78 | HTT (0.39) | HTTPOLBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9712137 | 0.78 | ALDH1A1 (0.44) | HTTPOLBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL3795835 | 0.78 | POLB (0.39) | HTTPOLBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL27612200 | 0.78 | HTT (0.50) | HTTPOLBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL27593883 | 0.77 | HTT (0.42) | HTTPOLBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL5610844 | 0.77 | DHFR (0.44) | HTTPOLBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL42756 | 0.76 | ALDH1A1 (0.46) | HTTPOLBALDH1A1MAPTNOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0245864-A2 | Cyclohexanedimethanol/diamine mixtures as RIM extenders | THE DOW CHEMICAL COMPANY (US) | 1987-11-19 | — | — | EP | claimed |
| EP-0248254-A2 | Process for bonding laminates | MOBAY CORPORATION (US) | 1987-12-09 | — | — | EP | disclosed |
| EP-0185369-A2 | Polyamide-polyurea polymers | THE DOW CHEMICAL COMPANY (US) | 1986-06-25 | — | — | EP | disclosed |
| EP-0173888-A1 | A process for the production of polyurethane elastomers and an isocyanate-reactive composition to be used in this process | MOBAY CORPORATION (US) | 1986-03-12 | — | — | EP | disclosed |
| EP-0119471-A2 | An active hydrogen-containing composition which provides mold release properties to a molded article, and a process for preparing molded polymeric products from the active hydrogen-containing composition | THE DOW CHEMICAL COMPANY (US) | 1984-09-26 | — | — | EP | disclosed |
| EP-0093862-A1 | Polyurea reaction injection molded elastomers | TEXACO DEVELOPMENT CORPORATION (US) | 1983-11-16 | — | — | EP | disclosed |
| EP-0075130-A2 | Improved reaction injection molding process | THE DOW CHEMICAL COMPANY (US) | 1983-03-30 | — | — | EP | disclosed |
| EP-0033498-A1 | A process for preparing reaction injection molded polyurethane compositions employing aliphatic amine chain extenders | THE DOW CHEMICAL COMPANY (US) | 1981-08-12 | — | — | EP | disclosed |