Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10772007 | 0.86 | HTT (0.39) | HTTPOLBALDH1A1MAPTNOS3 | |
| SCHEMBL117142 | 0.82 | HTT (0.46) | HTTPOLBALDH1A1MAPTNOS3 | |
| SCHEMBL27612200 | 0.82 | HTT (0.50) | HTTPOLBALDH1A1MAPTNOS3 | |
| SCHEMBL393744 | 0.78 | HTT (0.43) | HTTPOLBALDH1A1MAPTNOS3 | |
| SCHEMBL3802981 | 0.76 | HTT (0.42) | HTTPOLBALDH1A1MAPTNOS3 | |
| SCHEMBL1334971 | 0.76 | HTT (0.42) | HTTPOLBALDH1A1MAPTNOS3 | |
| SCHEMBL26865350 | 0.74 | ALDH1A1 (0.42) | HTTPOLBALDH1A1MAPTNOS3 | |
| SCHEMBL15629841 | 0.74 | POLB (0.34) | HTTPOLB | |
| SCHEMBL3795835 | 0.73 | POLB (0.39) | HTTPOLBALDH1A1MAPTNOS3 | |
| SCHEMBL3802566 | 0.73 | HTT (0.39) | HTTPOLBALDH1A1MAPTNOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106935-A | Quasiprepolymer of polycarbonate- or -etherurethanes; polyureas | TEXACO CHEMICAL COMPANY (US) | 1992-04-21 | — | — | US | disclosed |
| EP-0175447-A1 | Process for the production of reaction injection molded elastomers | TEXACO DEVELOPMENT CORPORATION (US) | 1986-03-26 | — | — | EP | disclosed |
| EP-0173888-A1 | A process for the production of polyurethane elastomers and an isocyanate-reactive composition to be used in this process | MOBAY CORPORATION (US) | 1986-03-12 | — | — | EP | disclosed |