SCHEMBL107723

SCHEMBL107723

O=C(O)C(S)CC(O)CO

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RNPEP Q9H4A4 3/20 0.52
LMNA P02545 3/20 0.43
OR51E2 Q9H255 1/20 0.42
FOLH1 Q04609 1/20 0.41
ALDH1A1 P00352 2/20 0.38
HPGD P15428 2/20 0.35
HSD17B10 Q99714 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
ABCB11 O95342 1/20 0.35
F2 P00734 1/20 0.35
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
MAPT P10636 1/20 0.35
ALOX15 P16050 1/20 0.35
KMT2A Q03164 1/20 0.35
DUSP3 P51452 1/20 0.35
PTPN5 P54829 1/20 0.35
PTPN11 Q06124 1/20 0.35
CYP2C9 P11712 1/20 0.35
HIF1A Q16665 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thioglycolic Acid SCHEMBL31621882 0.91 RNPEP (0.45) RNPEPLMNAOR51E2FOLH1ALDH1A1
SCHEMBL3093445 0.78 RNPEP (0.68) RNPEPLMNAOR51E2FOLH1ALDH1A1
Glycerin SCHEMBL10580390 0.76 RNPEP (0.43) RNPEPLMNAOR51E2FOLH1ALDH1A1
SCHEMBL17635909 0.76 OR51E2 (0.48) LMNAOR51E2ALDH1A1CYP2C9PDE4A
Glycerin SCHEMBL7795652 0.76 LMNA (0.53) RNPEPLMNAOR51E2FOLH1ALDH1A1
SCHEMBL902591 0.75
Monothioglycerol SCHEMBL812749 0.75 LMNA (0.65) LMNAOR51E2FOLH1ALDH1A1HPGD
SCHEMBL6838473 0.74 OR51E2 (0.60) LMNAOR51E2ALDH1A1PDE4ASLC1A1
SCHEMBL5902879 0.74 OR51E2 (0.60) LMNAOR51E2ALDH1A1PDE4ASLC1A1
SCHEMBL6838468 0.74 OR51E2 (0.60) LMNAOR51E2ALDH1A1PDE4ASLC1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 180 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4382172-B1 COMPOSITION FOR PERMANENT SHAPING OF HUMAN HAIR KAO GERMANY GMBH (DE) 2026-03-11 EP claimed
EP-4382172-A1 COMPOSITION FOR PERMANENT SHAPING OF HUMAN HAIR Kao Germany GmbH (DE) 2024-06-12 EP claimed
EP-2490727-B1 COMPOSITION FOR THE TREATMENT OF A BONE FRACTURE BIOMEDICAL BONDING AB (SE) 2020-09-23 EP claimed
US-9795558-B2 Depilatory formulations and methods of using same RECKITT & COLMAN (OVERSEAS) LIMITED (GB) 2017-10-24 US claimed
EP-2424490-B1 COMPOSITION FOR PERMANENT SHAPING OF HUMAN HAIR KAO GERMANY GMBH (DE) 2017-06-28 EP claimed
US-9642783-B2 Depilatory compositions L'OREAL (FR) 2017-05-09 US claimed
EP-2575742-B1 IMPROVEMENTS IN OR RELATING TO DEPILATORY COMPOSITIONS RECKITT & COLMAN OVERSEAS (GB) 2016-11-02 EP claimed
US-20160000484-A1 COMPOSITION FOR THE TREATMENT OF A BONE FRACTURE REPAIR TECHNOLOGIES SWEDEN AB (SE) 2016-01-07 US claimed
US-9205037-B2 Single phase depilatory composition CHURCH & DWIGHT CO., INC. (US) 2015-12-08 US claimed
US-20150283042-A1 DEPILATORY COMPOSITIONS L'OREAL (FR) 2015-10-08 US claimed
EP-1001735-A1 DEPILATORY COMPOSITIONS, METHODS FOR THEIR PREPARATION AND THEIR USE Reckitt & Colman France (FR) 2000-05-24 EP claimed
WO-1999002125-A1 DEPILATORY COMPOSITIONS, METHODS FOR THEIR PREPARATION AND THEIR USE RECKITT & COLMAN FRANCE (FR) 1999-01-21 WO claimed
EP-0672405-A1 Hair treatment composition KAO CORPORATION (JP) 1995-09-20 EP claimed
EP-0363057-B1 Permanent wave solution REDKEN LABORATORIES INC (US) 1994-04-06 EP claimed
US-5241973-A Mercaptopolyoxyethylene compound as posttreatment or additive; durability SHISEIDO (JP) 1993-09-07 US claimed
EP-0529437-A1 Hair treatment composition Kao Corporation (JP) 1993-03-03 EP claimed
US-5093113-A Water, glyceryl thioglycolate, emulsifier, immiscible layers SHISEIDO CO., LTD. (JP) 1992-03-03 US claimed
US-4841997-A APPLYING REDUCING AGENT FOR KERATIN DISULFIDE BONDS, REFORMING, THEN USING IONIC WATER-SOLUBLE SETTING AGENT; PERMANENT WAVES PETROW HENRY G (US) 1989-06-27 US claimed
US-4816246-A AMMONIUM THIOGLYCOLATE REDKEN LABORATORIES, INC. (US) 1989-03-28 US claimed
EP-0288151-A2 Permanent wave composition L'OREAL, S.A. (FR) 1988-10-26 EP claimed