SCHEMBL4138200

SCHEMBL4138200

O=C(O)C(CC(O)CO)C(CC(O)CO)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
OR51E2 Q9H255 1/20 0.46
LMNA P02545 2/20 0.42
ALDH1A1 P00352 1/20 0.42
TDP1 Q9NUW8 1/20 0.39
PDE4A P27815 1/20 0.37
SLC1A1 P43005 2/20 0.36
SLC22A6 Q4U2R8 1/20 0.35
THRB P10828 1/20 0.35
USP2 O75604 2/20 0.34
SLC1A3 P43003 1/20 0.34
SLC1A2 P43004 1/20 0.34
SLCO1B1 Q9Y6L6 1/20 0.34
TSHR P16473 2/20 0.33
CYP2C9 P11712 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19921751 0.85 SLC1A3 (0.39) OR51E2LMNAALDH1A1TDP1PDE4A
SCHEMBL17635909 0.80 OR51E2 (0.48) OR51E2LMNAALDH1A1PDE4ASLC1A1
SCHEMBL6838474 0.78 OR51E2 (0.60) OR51E2LMNAALDH1A1PDE4ASLC1A1
SCHEMBL2059956 0.78 OR51E2 (0.60) OR51E2LMNAALDH1A1PDE4ASLC1A1
SCHEMBL6838468 0.78 OR51E2 (0.60) OR51E2LMNAALDH1A1PDE4ASLC1A1
SCHEMBL6839516 0.78 OR51E2 (0.60) OR51E2LMNAALDH1A1PDE4ASLC1A1
SCHEMBL5902879 0.78 OR51E2 (0.60) OR51E2LMNAALDH1A1PDE4ASLC1A1
SCHEMBL6838473 0.78 OR51E2 (0.60) OR51E2LMNAALDH1A1PDE4ASLC1A1
SCHEMBL21819964 0.76 USP2 (0.40) THRBUSP2SMN1; SMN2CYP3A4
Ammonia Solution, Strong SCHEMBL8998366 0.76 SLC1A1 (0.44) OR51E2LMNAALDH1A1TDP1PDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1189687-B1 FLOWABLE W/O TYPE EMULSIONS WITH A HIGH WATER CONTENT CONTAINING MEDIUM POLAR LIPIDS BEIERSDORF AG (DE) 2005-01-19 EP claimed
EP-1189688-B1 W/O TYPE EMULSIONS WITH A HIGH WATER CONTENT CONTAINING MEDIUM POLAR LIPIDS BEIERSDORF AG (DE) 2004-12-29 EP claimed
US-20250241839-A1 IMPROVE THE WATER RESISTANCE OF COSMETIC COMPOSITIONS COMPRISING PIGMENTS TOTALENERGIES ONETECH (FR) 2025-07-31 US disclosed
US-20250221915-A1 IMPROVEMENT OF THE WATER RESISTANCE OF COSMETIC COMPOSITIONS COMPRISING UV FILTERS TOTALENERGIES ONETECH (FR) 2025-07-10 US disclosed
EP-4577310-A1 HAIR CARE COMPOSITIONS LEADING TO AN INCREASE OF THE COLOUR RESISTANCE OF DYED HAIR DSM IP Assets B.V. (NL) 2025-07-02 EP disclosed
EP-4504131-A1 IMPROVE THE WATER RESISTANCE OF COSMETIC COMPOSITIONS COMPRISING PIGMENTS DSM IP Assets B.V. (NL) 2025-02-12 EP disclosed
EP-4504132-A1 IMPROVEMENT OF THE WATER RESISTANCE OF COSMETIC COMPOSITIONS COMPRISING UV FILTERS DSM IP Assets B.V. (NL) 2025-02-12 EP disclosed
US-20240293297-A1 EYEBROW PRIMER L’ORÉAL (FR) 2024-09-05 US disclosed
WO-2024042024-A1 HAIR CARE COMPOSITIONS LEADING TO AN INCREASE OF THE COLOUR RESISTANCE OF DYED HAIR DSM IP ASSETS B.V. (NL) 2024-02-29 WO disclosed
US-20230346656-A1 EYEBROW PRIMER L'ORÉAL (FR) 2023-11-02 US disclosed
WO-2023194290-A1 IMPROVEMENT OF THE WATER RESISTANCE OF COSMETIC COMPOSITIONS COMPRISING UV FILTERS DSM IP ASSETS B.V. (NL) 2023-10-12 WO disclosed
WO-2023194289-A1 IMPROVE THE WATER RESISTANCE OF COSMETIC COMPOSITIONS COMPRISING PIGMENTS DSM IP ASSETS B.V. (NL) 2023-10-12 WO disclosed
EP-2623094-A1 Use of an edelweiss extract DSM IP Assets B.V. (NL) 2013-08-07 EP disclosed
US-20090087462-A1 Use of pyrimidine derivatives for cosmetic purposes TREMBLEY MARCELLA 2009-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250221915-A1 IMPROVEMENT OF THE WATER RESISTANCE OF COSMETIC COMPOSITIONS COMPRISING UV FILTERS C1R, CAPRIN1, CYP51A1 OR51E2 2597/4885LMNA 750/4885ALDH1A1 1512/4885
US-20250241839-A1 IMPROVE THE WATER RESISTANCE OF COSMETIC COMPOSITIONS COMPRISING PIGMENTS FASN, FDFT1, SCD5 OR51E2 1232/4885LMNA 1029/4885ALDH1A1 1348/4885
US-20090087462-A1 Use of pyrimidine derivatives for cosmetic purposes TYMP, TYMS, UNG OR51E2 4308/4885LMNA 1675/4885ALDH1A1 1067/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.