Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | ESR1 | P03372 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6067577 | 0.93 | ESR1 (0.47) | TDP1ALDH1A1ESR1ESR2MAPT | |
| SCHEMBL16684723 | 0.90 | TDP1 (0.56) | TDP1ALDH1A1ESR1L3MBTL1MAPT | |
| SCHEMBL2978166 | 0.88 | TDP1 (0.61) | TDP1ALDH1A1ESR1L3MBTL1ESR2 | |
| SCHEMBL8385248 | 0.86 | ESR1 (0.59) | TDP1ALDH1A1ESR1ESR2MAPT | |
| SCHEMBL14803622 | 0.85 | KDM4E (0.54) | TDP1ALDH1A1ESR1ESR2MAPT | |
| SCHEMBL22418 | 0.85 | TDP1 (0.59) | TDP1ALDH1A1ESR1ESR2MAPT | |
| SCHEMBL31298566 | 0.85 | TDP1 (0.59) | TDP1ALDH1A1ESR1ESR2MAPT | |
| SCHEMBL12376808 | 0.85 | ESR1 (0.41) | TDP1ALDH1A1ESR1ESR2MAPT | |
| SCHEMBL13567324 | 0.85 | RAB9A (0.47) | TDP1ALDH1A1ESR1ESR2MAPT | |
| SCHEMBL6470038 | 0.83 | TDP1 (0.56) | TDP1ALDH1A1ESR1ESR2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4696710-A | REFRCTORY FIBERS; DISSOLVING, SINTERING | CERAMIQUES ET COMPOSITES, LES MIROIRS, LA DEFENSE 3 - 92400 COURBEVOIE, FRANCE | 1987-09-29 | — | — | US | disclosed |