Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6470038 | 0.95 | TDP1 (0.56) | TDP1LMNAMAPK1HIF1ASLC6A2 | |
| SCHEMBL6067577 | 0.91 | ESR1 (0.47) | TDP1LMNAMAPK1SLC6A2KMT2A | |
| SCHEMBL14803622 | 0.90 | KDM4E (0.54) | TDP1LMNAESR1ESR2NPC1 | |
| SCHEMBL216569 | 0.90 | TDP1 (0.73) | TDP1LMNAMAPK1HIF1ASLC6A2 | |
| SCHEMBL10773147 | 0.88 | TDP1 (0.46) | TDP1LMNAMAPK1SLC6A2ESR1 | |
| SCHEMBL4624467 | 0.88 | SERPINE1 (0.47) | TDP1LMNAKMT2AALDH1A1SMN1; SMN2 | |
| Propene SCHEMBL4012587 | 0.85 | LMNA (0.67) | TDP1LMNAMAPK1HIF1ASLC6A2 | |
| Propene SCHEMBL6062789 | 0.85 | LMNA (0.67) | TDP1LMNAMAPK1HIF1ASLC6A2 | |
| Propene SCHEMBL4455281 | 0.85 | LMNA (0.67) | TDP1LMNAMAPK1HIF1ASLC6A2 | |
| Propene SCHEMBL6431713 | 0.85 | LMNA (0.67) | TDP1LMNAMAPK1HIF1ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113583372-A | Preparation method and application of single molecular chain nano-particles | 中国科学院化学研究所 | 2021-11-02 | — | — | CN | claimed |
| US-3933509-A | Photo-polymerizable composition containing an acid salt of an indolinobenzospiropyran | FUJI PHOTO FILM CO., LTD. (JA) | 1976-01-20 | — | — | US | claimed |
| US-20250188071-A1 | MODULATORS OF THE INTEGRATED STRESS RESPONSE PATHWAY | EVOTEC INTERNATIONAL GMBH (DE) | 2025-06-12 | — | — | US | disclosed |
| US-12258338-B2 | Modulators of the integrated stress response pathway | EVOTEC INTERNATIONAL GMBH (DE) | 2025-03-25 | — | — | US | disclosed |
| CN-115919859-B | Pharmaceutical composition of heteroaryl derivative and application of pharmaceutical composition in medicine | 四川海思科制药有限公司 | 2024-01-05 | — | — | CN | disclosed |
| US-11667733-B2 | Polyvinyl esters and methods related thereto | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2023-06-06 | — | — | US | disclosed |
| US-11667733-B2 | Polyvinyl esters and methods related thereto | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2023-06-06 | — | — | US | disclosed |
| CN-115919859-A | Pharmaceutical composition of heteroaryl derivative and application thereof in medicine | 四川海思科制药有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-115135307-A | Carrier for cell delivery | 株式会社ITO | 2022-09-30 | — | — | CN | disclosed |
| US-20220227747-A1 | MODULATORS OF THE INTEGRATED STRESS RESPONSE PATHWAY | EVOTEC (UK) LIMITED (GB) | 2022-07-21 | — | — | US | disclosed |
| CN-113583372-B | Preparation method and application of single molecular chain nano-particles | 中国科学院化学研究所 | 2022-04-01 | — | — | CN | disclosed |
| EP-0464704-A1 | Fluorine-containing copolymer and the curable composition containing the same | DAIKIN INDUSTRIES, LIMITED (JP) | 1992-01-08 | — | — | EP | disclosed |
| US-5026799-A | Halogenated aliphatic acids or zinc salts therof | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-06-25 | — | — | US | disclosed |
| US-4880873-A | HEAT RESISTANT MODIFIED ETHYLENE VINYL ALCOHOL COPOLYMERS | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1989-11-14 | — | — | US | disclosed |
| US-4847242-A | ANTIBIOTICS | BEECHAM GROUP P.L.C. (GB) | 1989-07-11 | — | — | US | disclosed |
| EP-0143380-B1 | PHOTORESIST COMPOSITION | CIBA-GEIGY AG (CH) | 1989-02-15 | — | — | EP | disclosed |
| US-4696988-A | Process for preparation of reactive polymers and polymers prepared by said process | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-09-29 | — | — | US | disclosed |
| EP-0181094-A1 | Adhesive for chlorine-containing polymers and aromatic group-containing polymers | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1986-05-14 | — | — | EP | disclosed |
| EP-0143380-A2 | Photoresist composition | CIBA-GEIGY AG (CH) | 1985-06-05 | — | — | EP | disclosed |
| US-3933509-A | Photo-polymerizable composition containing an acid salt of an indolinobenzospiropyran | FUJI PHOTO FILM CO., LTD. (JA) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12258338-B2 | Modulators of the integrated stress response pathway | CRHR2, CRHR1, CRH | TDP1 1966/4885LMNA 2766/4885MAPK1 745/4885 |
| US-20250188071-A1 | MODULATORS OF THE INTEGRATED STRESS RESPONSE PATHWAY | CRHR2, CRHR1, CRH | TDP1 1966/4885LMNA 2766/4885MAPK1 745/4885 |
| US-20220227747-A1 | MODULATORS OF THE INTEGRATED STRESS RESPONSE PATHWAY | CRHR2, CRHR1, CRH | TDP1 1966/4885LMNA 2766/4885MAPK1 745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.