Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SCN4A | P35499 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11259813 | 0.76 | MTNR1A (0.50) | PPARGPPARATHRBLMNAMTNR1A | |
| SCHEMBL10869922 | 0.75 | PPARG (0.49) | PPARGPPARALMNAMTNR1AMTNR1B | |
| SCHEMBL11795671 | 0.74 | LMNA (0.47) | THRBLMNAMTNR1AMTNR1BKDM4E | |
| SCHEMBL5936455 | 0.72 | PPARA (0.52) | PPARGPPARATHRBLMNAMTNR1A | |
| SCHEMBL23239453 | 0.71 | LMNA (0.53) | LMNAMTNR1AMTNR1BSMN1; SMN2KDM4E | |
| SCHEMBL3085599 | 0.71 | CYP2C19 (0.45) | PPARGPPARA | |
| Acrylic Acid SCHEMBL28572105 | 0.70 | LMNA (0.52) | THRBLMNASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL10357756 | 0.70 | PPARG (0.54) | PPARGPPARATHRBLMNAMTNR1A | |
| SCHEMBL7249737 | 0.70 | PPARG (0.50) | PPARGPPARATHRBLMNAMTNR1A | |
| SCHEMBL1538038 | 0.69 | PPARG (0.81) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0243774-A1 | Substituted quinoxalinyloxy-phenoxypropionic-acid derivatives | BAYER AG (DE) | 1987-11-04 | — | — | EP | disclosed |