Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | HTR6 | P50406 | 5/20 | 0.59 |
| ▸ | CA1 | P00915 | 2/20 | 0.59 |
| ▸ | CA2 | P00918 | 2/20 | 0.59 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | AURKA | O14965 | 1/20 | 0.49 |
| ▸ | DHFR | P00374 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | IL1RN | P18510 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL965226 | 0.85 | KEAP1 (0.66) | KMT2AHTR6CA1CA2KEAP1 | |
| SCHEMBL5046841 | 0.84 | HSD17B2 (0.55) | KMT2ACA1CA2KEAP1HTT | |
| SCHEMBL5041834 | 0.84 | MEN1 (0.55) | KMT2ACA1CA2KEAP1MEN1 | |
| SCHEMBL3332937 | 0.84 | CA12 (0.65) | KMT2ACA1CA2KEAP1HTT | |
| SCHEMBL28821888 | 0.84 | UQCRB (0.54) | KMT2ACA1CA2KEAP1HTT | |
| SCHEMBL751419 | 0.84 | CYP19A1 (0.63) | KMT2AKEAP1MEN1ALDH1A1PRMT1 | |
| SCHEMBL5040134 | 0.83 | ALDH1A1 (0.50) | KMT2ACA1CA2KEAP1CA9 | |
| SCHEMBL9811664 | 0.83 | POLB (0.68) | KMT2AHTR6CA1CA2KEAP1 | |
| SCHEMBL5036917 | 0.83 | UQCRB (0.56) | KMT2ACA1CA2KEAP1HTT | |
| SCHEMBL5044522 | 0.81 | CYP19A1 (0.55) | KMT2AMEN1ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4668667-A | ANTICHOLESTEROL AGENTS | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1987-05-26 | — | — | US | disclosed |