Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | THPO | P40225 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | GMNN | O75496 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10770978 | 0.82 | DRD2 (0.40) | MEN1MAPK1KMT2AKDM4EHTR2A | |
| Hydrochloric Acid SCHEMBL10570034 | 0.77 | MEN1 (0.38) | CYP3A4CYP2D6CYP2C9NFKB1THPO | |
| SCHEMBL10771892 | 0.77 | LMNA (0.53) | LMNAKDM4E | |
| Hydrochloric Acid SCHEMBL10772441 | 0.77 | LMNA (0.44) | CYP3A4CYP2D6CYP2C9NFKB1MEN1 | |
| SCHEMBL10710825 | 0.76 | KDM4E (0.40) | MEN1KMT2AKDM4EDRD2 | |
| Hydrochloric Acid SCHEMBL9829515 | 0.76 | KMT2A (0.40) | CYP3A4CYP2D6CYP2C9NFKB1THPO | |
| Hydrochloric Acid SCHEMBL10770827 | 0.75 | MEN1 (0.35) | CYP3A4CYP2D6CYP2C9NFKB1THPO | |
| Iprotiazem SCHEMBL10855448 | 0.75 | HTR1A (0.40) | MEN1KMT2AKDM4EDRD2HTR1A | |
| Iprotiazem SCHEMBL2110235 | 0.75 | HTR1A (0.40) | MEN1KMT2AKDM4EDRD2HTR1A | |
| Hydrochloric Acid SCHEMBL10573477 | 0.74 | ABCB1 (0.39) | CYP3A4CYP2D6CYP2C9MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0244723-A2 | Benzothiazinone derivatives, process for their preparation, medicaments containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-11-11 | — | — | EP | disclosed |