Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NT5E | P21589 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | PGK1 | P00558 | 1/20 | 0.39 |
| ▸ | PGK2 | P07205 | 1/20 | 0.39 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.39 |
| ▸ | HSPA8 | P11142 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2,6-Diaminopurine SCHEMBL8153506 | 1.00 | HIF1A (0.42) | HIF1ALMNANT5EADORA2AADORA2B | |
| 6-Chloroguanine SCHEMBL10674719 | 0.88 | LMNA (0.40) | HIF1ALMNANT5EADORA2AADORA2B | |
| Methylguanine SCHEMBL28389022 | 0.84 | ADORA3 (0.39) | LMNAADORA2AADORA2BADORA3ADORA1 | |
| Adenine SCHEMBL14636444 | 0.84 | HIF1A (0.49) | HIF1AADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL1994115 | 0.81 | HIF1A (0.43) | HIF1ALMNANT5EADORA2AADORA2B | |
| SCHEMBL240028 | 0.81 | HIF1A (0.43) | HIF1ALMNANT5EADORA2AADORA2B | |
| SCHEMBL9393256 | 0.81 | HIF1A (0.43) | HIF1ALMNANT5EADORA2AADORA2B | |
| SCHEMBL4436402 | 0.81 | HIF1A (0.43) | HIF1ALMNANT5EADORA2AADORA2B | |
| SCHEMBL5182595 | 0.81 | HIF1A (0.43) | HIF1ALMNANT5EADORA2AADORA2B | |
| SCHEMBL15263324 | 0.81 | HIF1A (0.43) | HIF1ALMNANT5EADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233493-A2 | Process for producing ribonucleosides | Yamasa Shoyu Kabushiki Kaisha (JP) | 1987-08-26 | — | — | EP | disclosed |