Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HBB | P68871 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PGK1 | P00558 | 1/20 | 0.38 |
| ▸ | PGK2 | P07205 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ribose (Furanose) SCHEMBL2497745 | 0.88 | LMNA (0.49) | LMNATP53GMNNNFKB1BLM | |
| 2,6-Diaminopurine SCHEMBL10774599 | 0.88 | HIF1A (0.42) | LMNATP53ALDH1A1GMNNNFKB1 | |
| 2,6-Diaminopurine SCHEMBL8153506 | 0.88 | HIF1A (0.42) | LMNATP53ALDH1A1GMNNNFKB1 | |
| Ribose (Furanose) SCHEMBL4542668 | 0.84 | ADK (0.40) | LMNATP53GMNNNFKB1BLM | |
| Ribose (Furanose) SCHEMBL2505730 | 0.84 | ADK (0.40) | LMNATP53GMNNNFKB1BLM | |
| Methylguanine SCHEMBL28389022 | 0.82 | ADORA3 (0.39) | LMNATP53ALDH1A1GMNNNFKB1 | |
| 6-Chloroguanine SCHEMBL7208346 | 0.81 | DPP4 (0.61) | LMNATP53ALDH1A1GMNNNFKB1 | |
| Ribose (Furanose) SCHEMBL10680212 | 0.79 | LMNA (0.37) | LMNATP53ALDH1A1GMNNNFKB1 | |
| SCHEMBL9657336 | 0.79 | LMNA (0.44) | LMNATP53GMNNNFKB1BLM | |
| 6-Chloroguanine SCHEMBL12813167 | 0.79 | LMNA (0.49) | LMNATP53ALDH1A1GMNNNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4728736-A | HERPES VIRUS | SOUTHERN RESEARCH INSTITUTE (US) | 1988-03-01 | — | — | US | disclosed |
| US-4543255-A | Carbocyclic analogs of purine 2'-deoxyribofuranosides | SOUTHERN RESEARCH INSTITUTE (US) | 1985-09-24 | — | — | US | disclosed |