Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GRM8 | O00222 | 2/20 | 0.37 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10774163 | 0.87 | KDM4E (0.44) | LMNATP53MAPTKDM4EALDH1A1 | |
| SCHEMBL10778317 | 0.81 | KDM4E (0.37) | LMNATP53MAPTKDM4EALDH1A1 | |
| SCHEMBL10778349 | 0.80 | ALDH1A1 (0.35) | LMNATP53MAPTKDM4EALDH1A1 | |
| SCHEMBL9792974 | 0.78 | KDM4E (0.53) | HTTLMNATP53KDM4EALDH1A1 | |
| SCHEMBL10774016 | 0.78 | HTR6 (0.41) | LMNATP53MAPTKDM4EALDH1A1 | |
| SCHEMBL10667098 | 0.77 | TSHR (0.45) | CYP1A2TP53CYP2C9KDM4EALDH1A1 | |
| SCHEMBL10775013 | 0.76 | MAPT (0.46) | HTTLMNATP53MAPTKDM4E | |
| SCHEMBL10774102 | 0.75 | HTR6 (0.44) | LMNATP53MAPTKDM4EALDH1A1 | |
| SCHEMBL10665580 | 0.74 | TSHR (0.47) | HTTALDH1A1 | |
| SCHEMBL10774291 | 0.74 | ALDH1A1 (0.47) | HTTLMNATP53KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0244097-A2 | Pyrazolopyrimidine herbicides | SCHERING AGROCHEMICALS LIMITED (GB) | 1987-11-04 | — | — | EP | claimed |
| EP-0244097-A2 | Pyrazolopyrimidine herbicides | SCHERING AGROCHEMICALS LIMITED (GB) | 1987-11-04 | — | — | EP | disclosed |