Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CCR4 | P51679 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.35 |
| ▸ | PFKFB4 | Q16877 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TCF4 | P15884 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10774163 | 0.92 | KDM4E (0.44) | KDM4EHSD17B10ALDH1A1HPGDLMNA | |
| SCHEMBL10778349 | 0.91 | ALDH1A1 (0.35) | KDM4EHSD17B10ALDH1A1HPGDCASP1 | |
| SCHEMBL9792974 | 0.82 | KDM4E (0.53) | KDM4EHSD17B10ALDH1A1HPGDLMNA | |
| SCHEMBL10774016 | 0.82 | HTR6 (0.41) | KDM4EHSD17B10ALDH1A1HPGDLMNA | |
| SCHEMBL10774609 | 0.81 | HTT (0.43) | KDM4EALDH1A1HPGDLMNATP53 | |
| SCHEMBL10775013 | 0.80 | MAPT (0.46) | KDM4EHSD17B10ALDH1A1HPGDLMNA | |
| SCHEMBL10774102 | 0.79 | HTR6 (0.44) | KDM4EHSD17B10ALDH1A1HPGDLMNA | |
| SCHEMBL10774291 | 0.78 | ALDH1A1 (0.47) | KDM4EHSD17B10ALDH1A1HPGDLMNA | |
| SCHEMBL10780298 | 0.72 | KDM4E (0.43) | KDM4EHSD17B10ALDH1A1HPGDLMNA | |
| SCHEMBL10775876 | 0.72 | KDM4E (0.41) | KDM4EHSD17B10ALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0244097-A2 | Pyrazolopyrimidine herbicides | SCHERING AGROCHEMICALS LIMITED (GB) | 1987-11-04 | — | — | EP | disclosed |