Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.44 |
| ▸ | FADS1 | O60427 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14769778 | 0.69 | GRM2 (0.73) | GRM2FADS1 | |
| SCHEMBL8487733 | 0.66 | GRM2 (0.45) | GRM2FADS1 | |
| SCHEMBL17047646 | 0.66 | FAAH (0.42) | FAAHMGLLHSD11B1ALOX5MEN1 | |
| SCHEMBL27573667 | 0.66 | GRM2 (0.59) | GRM2FADS1 | |
| SCHEMBL14573697 | 0.64 | GRM2 (0.82) | GRM2FADS1 | |
| SCHEMBL14214167 | 0.64 | GRM2 (0.82) | GRM2FADS1 | |
| SCHEMBL3087781 | 0.63 | MAOA (0.71) | GRM2FADS1 | |
| SCHEMBL1032517 | 0.63 | MAOA (0.71) | GRM2FADS1 | |
| SCHEMBL1557298 | 0.63 | MAOA (0.71) | GRM2FADS1 | |
| SCHEMBL30063909 | 0.63 | MAOA (0.71) | GRM2FADS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904489-B1 | PROCESS FOR THE SYNTHESIS OF TRIAZOLES | RIB X PHARMACEUTICALS INC (US) | 2011-01-26 | — | — | EP | disclosed |