SCHEMBL17047646

SCHEMBL17047646

CC1=CC(O)N(c2cccc(F)c2)C1=O

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.42
MGLL Q99685 1/20 0.42
NOTUM Q6P988 1/20 0.40
ALDH1A1 P00352 2/20 0.40
POLB P06746 1/20 0.40
GAA P10253 1/20 0.40
MAPT P10636 1/20 0.40
HSD11B1 P28845 1/20 0.40
ALOX5 P09917 2/20 0.39
L3MBTL1 Q9Y468 3/20 0.38
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
TP53 P04637 1/20 0.38
PGR P06401 1/20 0.38
IDH1 O75874 1/20 0.36
RXFP1 Q9HBX9 1/20 0.36
METAP1 P53582 1/20 0.36
METAP2 P50579 1/20 0.35
MPI P34949 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17047672 0.82 FAAH (0.42) FAAHMGLLNOTUMALDH1A1POLB
SCHEMBL17047801 0.81 RXFP1 (0.43) MGLLNOTUMALDH1A1MAPTHSD11B1
SCHEMBL17047790 0.80 RXFP1 (0.38) ALDH1A1POLBGAAMAPTMEN1
SCHEMBL17047640 0.76 HTR7 (0.35) ALDH1A1GAA
SCHEMBL17047713 0.72 MEN1 (0.40) MGLLNOTUMALDH1A1POLBGAA
SCHEMBL4127465 0.71 MEN1 (0.42) FAAHMGLLNOTUMALDH1A1POLB
SCHEMBL4110694 0.66 NOTUM (0.40) FAAHMGLLNOTUMALDH1A1POLB
SCHEMBL1077612 0.66 GRM2 (0.44) FAAHMGLLHSD11B1ALOX5L3MBTL1
SCHEMBL16480422 0.65 ALOX5 (0.46) FAAHMGLLALDH1A1POLBGAA
SCHEMBL10578787 0.64 FAAH (0.50) FAAHMGLLNOTUMALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3110808-B1 PLANT GROWTH REGULATING COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2018-08-29 EP disclosed
US-9751867-B2 Plant growth regulating compounds SYNGENTA PARTICIPATIONS AG (CH) 2017-09-05 US disclosed
EP-3110808-A1 PLANT GROWTH REGULATING COMPOUNDS Syngenta Participations AG (CH) 2017-01-04 EP disclosed
US-20160368900-A1 PLANT GROWTH REGULATING COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2016-12-22 US disclosed
WO-2015128321-A1 PLANT GROWTH REGULATING COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2015-09-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160368900-A1 PLANT GROWTH REGULATING COMPOUNDS GHDC, GAK, EIF4G2 FAAH 1983/4885MGLL 729/4885NOTUM 2863/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.