Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4580436 | 0.79 | MAOA (0.43) | MAOAALDH1A1SMN1; SMN2GSK3BKDM1A | |
| SCHEMBL1156077 | 0.79 | MAOA (0.43) | MAOAALDH1A1SMN1; SMN2GSK3BKDM1A | |
| SCHEMBL12264201 | 0.78 | MAOA (0.46) | MAOAALDH1A1SMN1; SMN2GSK3BKDM1A | |
| SCHEMBL29814962 | 0.77 | MAOA (0.45) | MAOAALDH1A1SMN1; SMN2GSK3BKDM1A | |
| SCHEMBL347425 | 0.77 | MAOA (0.45) | MAOAALDH1A1SMN1; SMN2GSK3BKDM1A | |
| SCHEMBL16728889 | 0.77 | MAOA (0.45) | MAOAALDH1A1SMN1; SMN2GSK3BKDM1A | |
| SCHEMBL1412732 | 0.75 | MAOA (0.43) | MAOAALDH1A1SMN1; SMN2GSK3BKDM1A | |
| SCHEMBL32662573 | 0.75 | MAOA (0.43) | MAOAALDH1A1SMN1; SMN2GSK3BKDM1A | |
| SCHEMBL31571121 | 0.75 | MAOA (0.43) | MAOAALDH1A1SMN1; SMN2GSK3BKDM1A | |
| SCHEMBL7138108 | 0.75 | MAOA (0.43) | MAOAALDH1A1SMN1; SMN2GSK3BKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0249909-A1 | Tricyclic penam compounds, their production and their use | Takeda Chemical Industries, Ltd. (JP) | 1987-12-23 | — | — | EP | disclosed |