Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | PYGL | P06737 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10671137 | 0.88 | SCN9A (0.43) | P2RX4SCN9AATMALDH1A1LMNA | |
| SCHEMBL10799486 | 0.86 | NPC1 (0.53) | P2RX4SCN9AALDH1A1LMNAHPGD | |
| SCHEMBL10773470 | 0.84 | TRPM8 (0.46) | P2RX4SCN9AALDH1A1LMNAHPGD | |
| SCHEMBL10775341 | 0.84 | SCN9A (0.45) | P2RX4SCN9AALDH1A1LMNAHPGD | |
| SCHEMBL10774758 | 0.83 | SCN9A (0.48) | P2RX4SCN9AALDH1A1LMNAHPGD | |
| SCHEMBL10775726 | 0.83 | SCN9A (0.53) | P2RX4SCN9AALDH1A1LMNAHPGD | |
| SCHEMBL10507521 | 0.82 | ALDH1A1 (0.40) | P2RX4SCN9AALDH1A1LMNAHPGD | |
| SCHEMBL10772743 | 0.82 | SCN9A (0.46) | P2RX4SCN9AALDH1A1LMNAKMT2A | |
| SCHEMBL10804369 | 0.81 | SCN9A (0.49) | P2RX4SCN9AALDH1A1LMNAHPGD | |
| SCHEMBL10671776 | 0.80 | EPHX1 (0.44) | P2RX4SCN9AALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0131071-B1 | BENZOYLUREA COMPOUNDS, AND PESTICIDAL AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1987-05-13 | — | — | EP | claimed |
| US-4656193-A | Benzoylurea compounds, and insecticidal and acaricidal compositions comprising same | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1987-04-07 | — | — | US | claimed |
| EP-0131071-A1 | Benzoylurea compounds, and pesticidal and pharmaceutical compositions comprising same | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1985-01-16 | — | — | EP | claimed |
| EP-0131071-B1 | BENZOYLUREA COMPOUNDS, AND PESTICIDAL AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1987-05-13 | — | — | EP | disclosed |
| US-4656193-A | Benzoylurea compounds, and insecticidal and acaricidal compositions comprising same | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1987-04-07 | — | — | US | disclosed |
| EP-0131071-A1 | Benzoylurea compounds, and pesticidal and pharmaceutical compositions comprising same | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1985-01-16 | — | — | EP | disclosed |