Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.49 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.42 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10774758 | 0.86 | SCN9A (0.48) | NPC1RAB9AP2RX4TRPM8ALDH1A1 | |
| SCHEMBL10777366 | 0.86 | P2RX4 (0.46) | NPC1RAB9AP2RX4TRPM8ALDH1A1 | |
| SCHEMBL10778746 | 0.84 | NPC1 (0.53) | NPC1RAB9AP2RX4TRPM8ALDH1A1 | |
| SCHEMBL10776253 | 0.84 | NPC1 (0.46) | NPC1RAB9AP2RX4TRPM8ALDH1A1 | |
| SCHEMBL10771876 | 0.83 | SCN9A (0.49) | NPC1RAB9AP2RX4TRPM8ALDH1A1 | |
| SCHEMBL15533401 | 0.81 | TRPM8 (0.55) | P2RX4TRPM8ALDH1A1LMNAHPGD | |
| SCHEMBL10772950 | 0.81 | LMNA (0.44) | NPC1RAB9AP2RX4TRPM8ALDH1A1 | |
| SCHEMBL28983175 | 0.79 | ALDH1A1 (0.55) | NPC1RAB9AP2RX4TRPM8ALDH1A1 | |
| SCHEMBL10666468 | 0.79 | ALDH1A1 (0.53) | NPC1RAB9AP2RX4TRPM8ALDH1A1 | |
| SCHEMBL2450851 | 0.78 | ALDH1A1 (0.58) | NPC1RAB9AP2RX4TRPM8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4656193-A | Benzoylurea compounds, and insecticidal and acaricidal compositions comprising same | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1987-04-07 | — | — | US | disclosed |