Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10777564 | 0.84 | ADRA1A (0.59) | SIGMAR1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8974286 | 0.82 | SIGMAR1 (0.45) | SIGMAR1ADRB2LMNAHIF1ASLC6A2 | |
| Tibalosin SCHEMBL8974326 | 0.79 | SIGMAR1 (0.41) | SIGMAR1ADRB2LMNAHIF1ASLC6A2 | |
| Tibalosin SCHEMBL1254588 | 0.78 | SIGMAR1 (0.41) | SIGMAR1ADRB2LMNAHIF1ASLC6A2 | |
| SCHEMBL8974546 | 0.77 | SIGMAR1 (0.40) | SIGMAR1ADRB2LMNAHIF1ASLC6A2 | |
| SCHEMBL8974885 | 0.76 | ADRB1 (0.40) | SIGMAR1ADRB2LMNAHIF1ASLC6A2 | |
| SCHEMBL10776744 | 0.76 | GRIN2B (0.39) | SIGMAR1ADRB2LMNAHIF1ASLC6A2 | |
| SCHEMBL8974994 | 0.75 | SIGMAR1 (0.40) | SIGMAR1ADRB2LMNAHIF1ASLC6A2 | |
| SCHEMBL10779305 | 0.73 | SIGMAR1 (0.45) | SIGMAR1ADRB2LMNAHIF1ASLC6A2 | |
| SCHEMBL7381182 | 0.73 | SIGMAR1 (0.57) | SIGMAR1ADRB2LMNAHIF1ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4638070-A | HYPOTENSIVE | CONTINENTAL PHARMA (BE) | 1987-01-20 | — | — | US | disclosed |