Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL77732 | 0.91 | MEN1 (0.63) | MEN1KMT2AMAPTNPSR1HPGD | |
| SCHEMBL13552273 | 0.87 | MAPT (0.56) | MEN1KMT2AMAPTNPSR1HPGD | |
| SCHEMBL3430755 | 0.85 | MEN1 (0.58) | TP53MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL6005632 | 0.85 | MEN1 (0.58) | TP53MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL11772807 | 0.84 | MEN1 (0.56) | MEN1KMT2AMAPTNPSR1HPGD | |
| SCHEMBL6526695 | 0.84 | MEN1 (0.56) | MEN1KMT2AMAPT | |
| SCHEMBL6526697 | 0.84 | MEN1 (0.56) | MEN1KMT2AMAPT | |
| SCHEMBL15026365 | 0.84 | MEN1 (0.56) | MEN1KMT2AMAPT | |
| SCHEMBL28493126 | 0.83 | TP53 (0.51) | TP53MEN1KMT2AHDAC2 | |
| SCHEMBL28639399 | 0.81 | MEN1 (0.50) | TP53MEN1KMT2AMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0141140-B1 | BENZYLIDENE MALONIC ACID POLYESTERS, PROCESS FOR THEIR PREPARATION AND THE USE OF SUCH POLYESTERS IN THE STABILISATION OF THERMOPLASTIC RESINS AGAINST U.V. | BAYER AG (DE) | 1987-01-21 | — | — | EP | disclosed |
| US-4588807-A | ANTIASTHMA, ANTIULCERE, ANTICOAGULANT | BAYER AKTIENGESELLSCHAFT (DE) | 1986-05-13 | — | — | US | disclosed |
| EP-0141140-A1 | Benzylidene malonic acid polyesters, process for their preparation and the use of such polyesters in the stabilisation of thermoplastic resins against U.V. | BAYER AG (DE) | 1985-05-15 | — | — | EP | disclosed |