Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6526695 | 1.00 | MEN1 (0.56) | MEN1KMT2AMAPTSMN1; SMN2RECQL | |
| SCHEMBL15026365 | 1.00 | MEN1 (0.56) | MEN1KMT2AMAPTSMN1; SMN2RECQL | |
| SCHEMBL77732 | 0.92 | MEN1 (0.63) | MEN1KMT2AMAPTHTTAKR1C3 | |
| SCHEMBL3430755 | 0.87 | MEN1 (0.58) | MEN1KMT2AMAPTHTTAKR1C3 | |
| SCHEMBL6005632 | 0.87 | MEN1 (0.58) | MEN1KMT2AMAPTHTTAKR1C3 | |
| SCHEMBL11772807 | 0.85 | MEN1 (0.56) | MEN1KMT2AMAPTHTTAKR1C3 | |
| SCHEMBL979463 | 0.84 | ALDH1A1 (0.67) | MEN1KMT2AMAPTSMN1; SMN2RECQL | |
| SCHEMBL13552273 | 0.84 | MAPT (0.56) | MEN1KMT2AMAPT | |
| SCHEMBL28273258 | 0.84 | AKR1C3 (0.61) | MEN1KMT2AMAPTSMN1; SMN2RECQL | |
| SCHEMBL9401645 | 0.84 | KDM4E (0.52) | MEN1KMT2AMAPTALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130018049-A1 | Azaindole Compounds and Methods for Treating HIV | GLAXOSMITHKLINE LLC (US) | 2013-01-17 | — | — | US | disclosed |
| US-20050209117-A1 | Complexing agent for treating metallic and plastic surfaces | BASF AKTIENGESELLSCHAFT (DE) | 2005-09-22 | — | — | US | disclosed |
| EP-1023267-B1 | PYRIDYL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CERMOL SA (CH) | 2003-09-17 | — | — | EP | disclosed |
| US-6482841-B1 | Pyridyl compounds and pharmaceutical compositions containing them | CERMOL S.A. (CH) | 2002-11-19 | — | — | US | disclosed |
| EP-1023267-A1 | PYRIDYL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CERMOL S.A. (CH) | 2000-08-02 | — | — | EP | disclosed |
| US-5951841-A | ACIDIC ELECTROPLATING BATHS COMPRISING BRIGHTENERS FOR THE ELECTROLYTIC DEPOSITION OF METALLIC INORGANIC LAYERS ONTO SHAPED ARTICLES | BASF AKTIENGESELLSCHAFT (DE) | 1999-09-14 | — | — | US | disclosed |
| WO-1999019302-A1 | PYRIDYL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CERMOL S.A. (CH) | 1999-04-22 | — | — | WO | disclosed |
| US-5421990-A | An acidic aqueous electrodeposition bath having a nontoxic, nonirritating brightener comprising a benzylidine malonic ester or acetylacetonate | BASF AKTIENGESELLSCHAFT (DE) | 1995-06-06 | — | — | US | disclosed |
| CN-1010947-B | PROCESS FOR PREPN. OF PYRIDOPYRIMIDINES COMPOUNDS | BAYER AG (DE) | 1990-12-26 | — | — | CN | disclosed |
| EP-0381699-A1 | ALKYLENE AND DIALKYL KETALS AND ALKYL ALPHA-ENOL ETHERS OF ALPHA-ACETYL CINNAMIC ACIDS AND ESTERS THEREOF | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1990-08-16 | — | — | EP | disclosed |
| US-3951994-A | HYPOTENSIVE, CORONARY VESSEL DILATORS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-04-20 | — | — | US | disclosed |
| US-3951988-A | HYPOTENSIVE, CORONARY VESSEL DILATORS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-04-20 | — | — | US | disclosed |
| US-3948923-A | HYPOTENSIVE, VASODILATION | BAYER AKTIENGESELLSCHAFT (DT) | 1976-04-06 | — | — | US | disclosed |
| US-3946026-A | HYPOTENSIVE AGENTS, CORONARY VESSEL DILATORS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-03-23 | — | — | US | disclosed |
| US-3946028-A | HYPOTENSIVE AGENTS, CORONARY VESSEL DILATORS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-03-23 | — | — | US | disclosed |
| US-3946027-A | HYPOTENSIVE AGENTS, CORONARY VESSEL DILATORS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-03-23 | — | — | US | disclosed |
| US-3943140-A | HYPOTENSIVE, VASODILATION | BAYER AKTIENGESELLSCHAFT (DT) | 1976-03-09 | — | — | US | disclosed |
| US-3939171-A | HYPOTENSIVE, VASODILATION | BAYER AKTIENGESELLSCHAFT (DT) | 1976-02-17 | — | — | US | disclosed |
| US-3935220-A | VASODILATION, HYPOTENSIVE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-01-27 | — | — | US | disclosed |
| US-3935223-A | 2-Amino-1,4-dihydropyridine derivatives | BAYER AKTIENGESELLSCHAFT (DT) | 1976-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130018049-A1 | Azaindole Compounds and Methods for Treating HIV | AZI2, TPMT, INMT | MEN1 3932/4885KMT2A 298/4885MAPT 1502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.