SCHEMBL6005632

SCHEMBL6005632

COC(=O)/C(=C\c1ccccc1)C(=O)O

nearest known ligand 0.89

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.58
KMT2A Q03164 1/20 0.58
HTT P42858 1/20 0.56
TP53 P04637 1/20 0.53
AKR1C3 P42330 1/20 0.52
MAPT P10636 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3430755 1.00 MEN1 (0.58) MEN1KMT2AHTTTP53AKR1C3
SCHEMBL77732 0.94 MEN1 (0.63) MEN1KMT2AHTTAKR1C3MAPT
SCHEMBL6526697 0.87 MEN1 (0.56) MEN1KMT2AHTTAKR1C3MAPT
SCHEMBL11772807 0.87 MEN1 (0.56) MEN1KMT2AHTTAKR1C3MAPT
SCHEMBL15026365 0.87 MEN1 (0.56) MEN1KMT2AHTTAKR1C3MAPT
SCHEMBL6526695 0.87 MEN1 (0.56) MEN1KMT2AHTTAKR1C3MAPT
SCHEMBL13552273 0.86 MAPT (0.56) MEN1KMT2AMAPTNPSR1
SCHEMBL10777901 0.85 TP53 (0.65) MEN1KMT2ATP53MAPTNPSR1
SCHEMBL998238 0.85 MEN1 (0.54) MEN1KMT2AHTTTP53AKR1C3
SCHEMBL15426941 0.85 KDM4E (0.56) TP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240199851-A1 Improved Polymer Composition CELANESE POLYMERS HOLDING, INC. 2024-06-20 US disclosed
CN-118063856-A Flame retardant mixtures 科莱恩国际有限公司 2024-05-24 CN disclosed
CN-117897427-A Stabilizer combinations for preventing degradation of synthetic polymers 巴斯夫欧洲公司 2024-04-16 CN disclosed
EP-4334384-A1 IMPROVED POLYMER COMPOSITION DUPONT POLYMERS, INC. (US) 2024-03-13 EP disclosed
EP-4314141-A1 STABILIZER MIXTURE BASF SE (DE) 2024-02-07 EP disclosed
CN-117242131-A Flame retardant-stabilizer composition for thermoplastic polymers 科莱恩国际有限公司 2023-12-15 CN disclosed
US-20230314934-A1 PHOTOACTIVE COMPOUNDS, PHOTORESIST COMPOSITIONS INCLUDING THE SAME, AND PATTERN FORMATION METHODS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2023-10-05 US disclosed
US-20230314934-A1 PHOTOACTIVE COMPOUNDS, PHOTORESIST COMPOSITIONS INCLUDING THE SAME, AND PATTERN FORMATION METHODS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2023-10-05 US disclosed
CN-116547346-A Additive mixture 巴斯夫欧洲公司 2023-08-04 CN disclosed
CN-116268692-A Knitted textile and vamp and manufacturing method thereof 耐克创新有限合伙公司 2023-06-23 CN disclosed
EP-0898202-A1 Photogeneration of amines from alpha-aminoacetophenones Ciba SC Holding AG (CH) 1999-02-24 EP disclosed
EP-0665258-B1 Piperidenyle compounds and their use as a photostabilizer for polymers RHODIA CHIMIE SA (FR) 1998-07-01 EP disclosed
EP-0388321-B1 Piperidinyle compounds and their use as a photostabilizer for polymers RHONE POULENC CHIMIE (FR) 1996-12-18 EP disclosed
EP-0665258-A2 Piperidenyle compounds and their use as a photostabilizer for polymers RHONE-POULENC CHIMIE (FR) 1995-08-02 EP disclosed
EP-0365469-B1 Piperidine-triazine compounds for use as stabilizers for organic materials CIBA GEIGY AG (CH) 1994-02-02 EP disclosed
EP-0388321-A1 Piperidinyle compounds and their use as a photostabilizer for polymers RHONE-POULENC CHIMIE (FR) 1990-09-19 EP disclosed
EP-0365469-A1 Piperidine-triazine compounds for use as stabilizers for organic materials CIBA-GEIGY AG (CH) 1990-04-25 EP disclosed
US-RE31343-E STABILIZERS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1983-08-09 US disclosed
US-RE31342-E STABILIZERS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1983-08-09 US disclosed
US-4028334-A STABILIZERS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1977-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230314934-A1 PHOTOACTIVE COMPOUNDS, PHOTORESIST COMPOSITIONS INCLUDING THE SAME, AND PATTERN FORMATION METHODS CRY1, CBR3, C1S MEN1 1410/4885KMT2A 2240/4885HTT 3650/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.