SCHEMBL77732

SCHEMBL77732

COC(=O)C(=Cc1ccccc1)C(=O)OC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.63
KMT2A Q03164 1/20 0.63
MAPT P10636 2/20 0.54
NPSR1 Q6W5P4 1/20 0.54
HPGD P15428 1/20 0.53
AKR1C3 P42330 1/20 0.52
HTT P42858 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3430755 0.94 MEN1 (0.58) MEN1KMT2AMAPTNPSR1AKR1C3
SCHEMBL6005632 0.94 MEN1 (0.58) MEN1KMT2AMAPTNPSR1AKR1C3
SCHEMBL11772807 0.92 MEN1 (0.56) MEN1KMT2AMAPTNPSR1HPGD
SCHEMBL6526697 0.92 MEN1 (0.56) MEN1KMT2AMAPTAKR1C3HTT
SCHEMBL15026365 0.92 MEN1 (0.56) MEN1KMT2AMAPTAKR1C3HTT
SCHEMBL6526695 0.92 MEN1 (0.56) MEN1KMT2AMAPTAKR1C3HTT
SCHEMBL13552273 0.91 MAPT (0.56) MEN1KMT2AMAPTNPSR1HPGD
SCHEMBL10777901 0.91 TP53 (0.65) MEN1KMT2AMAPTNPSR1HPGD
SCHEMBL4732469 0.89 KMT2A (0.53) MEN1KMT2AMAPTNPSR1
SCHEMBL4732467 0.89 KMT2A (0.53) MEN1KMT2AMAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4426 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1582549-B1 Flame retardant resin blends based on polymers derived from 2-hydrocarbyl-3,3-Bis(4-Hydroxyaryl)Phthalimidine monomers SABIC INNOVATIVE PLASTICS IP (NL) 2011-03-09 EP claimed
CN-100509783-C Pheny(alkyl)carboxylic acid derivatives and dionic phenylalkylheterocyclic derivatives and their use as medicines with serum glucose and/or serum lipid lowering activity SIGMA TAU IND FARMACEUTI (IT) 2009-07-08 CN claimed
CN-1617854-A Pheny(alkyl)carboxylic acid derivatives and dionic phenylalkylheterocyclic derivatives and their use as medicines with serum glucose and/or serum lipid lowering activity SIGMA TAU IND FARMACEUTI (IT) 2005-05-18 CN claimed
US-5288750-A Antiulcer agents for gastrointestinal disorders ORION-YHTYMA OY (FI) 1994-02-22 US claimed
WO-1990002724-A1 SUBSTITUTED β-DIKETONES Orion-Yhtymä Oy (FI) 1990-03-22 WO claimed
US-4301209-A POLYESTER- OR -ETHERURETHANES ENDCAPPED WITH AN ACRYLIC COMPOUND AND A DIALKYL ESTER OF A P-ALKOXY BENZYLIDENE LAMINATION GAF CORPORATION (US) 1981-11-17 US claimed
US-6391949-B1 None US disclosed
EP-4747310-A1 NON-FLUORINATED POLYMER PROCESSING AIDS FOR DIE LIP BUILD-UP MITIGATION IN EXTRUSION OF COMPOSITIONS CONTAINING RECYCLED POLYETHYLENE Nova Chemicals (International) S.A. (CH) 2026-05-27 EP disclosed
EP-4536463-B1 PROCESS TO PREPARE THERMOPLASTIC COMPOSITIONS COMPRISING FLUORINE FREE POLYMER PROCESSING AIDS NOVA CHEMICALS INTERNATIONAL SA (CH) 2026-05-13 EP disclosed
US-12624133-B2 Solid catalyst component for polymerization of olefin and method for producing the same, catalyst for polymerization of olefin and method for producing the same, and method for producing polymer of olefin TOHO TITANIUM CO., LTD. (JP) 2026-05-12 US disclosed
EP-4731727-A1 HALF-WAVE PLATE Merck Patent GmbH (DE) 2026-04-29 EP disclosed
EP-4731708-A1 POLAR POLYMERS AS PROCESSING AIDS IN POLYETHYLENE Nova Chemicals (International) S.A. (CH) 2026-04-29 EP disclosed
EP-4728007-A1 NON-FLUORINATED POLYMER PROCESS AIDS Nova Chemicals (International) S.A. (CH) 2026-04-22 EP disclosed
US-3948854-A Salicylic acid hydrazide stabilizers for polymers CIBA-GEIGY CORPORATION (US) 1976-04-06 US disclosed
US-3944632-A Phosphoric acid anilides CIBA-GEIGY CORPORATION (US) 1976-03-16 US disclosed
US-3943096-A Use of hydroxyphenylurethanes for stabilising elastomers CIBA-GEIGY CORPORATION (US) 1976-03-09 US disclosed
US-3943098-A 1-Aza-4-thiacyclohexane-4,4-dioxide derivatives and their use as agents protecting against light rays CIBA-GEIGY CORPORATION (US) 1976-03-09 US disclosed
US-3943106-A POLYESTERS AND POLYAMIDS FROM HYDROXYBENZYLMALONIC ACID DERIVATIVES; STABILIZERS CIBA-GEIGY CORPORATION (US) 1976-03-09 US disclosed
US-3940363-A POLYMERS SANKYO COMPANY LIMITED (JA) 1976-02-24 US disclosed
US-3939175-A STABILIZER CIBA-GEIGY CORPORATION (US) 1976-02-17 US disclosed