Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 2/20 | 0.62 |
| ▸ | EGFR | P00533 | 2/20 | 0.58 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | SCN1A | P35498 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9694832 | 0.90 | MLYCD (0.72) | MLYCDEGFRERBB2TP53HPGD | |
| SCHEMBL10388616 | 0.89 | EGFR (0.60) | MLYCDEGFRERBB2HPGDHDAC1 | |
| SCHEMBL11711677 | 0.86 | MAPT (0.54) | MLYCDEGFRERBB2HPGDHDAC1 | |
| SCHEMBL18269325 | 0.86 | MAPT (0.54) | MLYCDEGFRERBB2HPGDHDAC1 | |
| SCHEMBL28278838 | 0.85 | MLYCD (0.62) | MLYCDEGFRERBB2TP53HPGD | |
| SCHEMBL13846249 | 0.84 | MLYCD (0.69) | MLYCDEGFRERBB2TP53HPGD | |
| SCHEMBL3081053 | 0.84 | HPGD (0.61) | MLYCDHPGDLMNACYP1A2CYP3A4 | |
| SCHEMBL4481559 | 0.84 | LMNA (0.58) | MLYCDEGFRERBB2HPGDLMNA | |
| SCHEMBL5123550 | 0.83 | NAMPT (0.48) | MLYCDEGFRERBB2LMNACYP1A2 | |
| SCHEMBL14117677 | 0.82 | CYP3A4 (0.43) | MLYCDEGFRERBB2HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0078845-B1 | ANTI-CONVULSANT | CLARK, Charles Randall (US) | 1987-02-04 | — | — | EP | claimed |
| EP-0078845-A4 | ANTI-CONVULSANT. | CLARK CHARLES RANDALL | 1983-09-02 | — | — | EP | claimed |
| EP-0078845-A1 | ANTI-CONVULSANT. | CLARK CHARLES RANDALL | 1983-05-18 | — | — | EP | claimed |
| US-4379165-A | Anti-convulsant | RESEARCH CORPORATION (US) | 1983-04-05 | — | — | US | claimed |
| WO-1982004046-A1 | ANTI-CONVULSANT | CLARK CHARLES RANDALL | 1982-11-25 | — | — | WO | claimed |
| EP-0078845-B1 | ANTI-CONVULSANT | CLARK, Charles Randall (US) | 1987-02-04 | — | — | EP | disclosed |
| US-4425327-A | Method of suppressing body odor with aminobenzoic acid amides | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1984-01-10 | — | — | US | disclosed |
| EP-0078845-A4 | ANTI-CONVULSANT. | CLARK CHARLES RANDALL | 1983-09-02 | — | — | EP | disclosed |
| EP-0078845-A1 | ANTI-CONVULSANT. | CLARK CHARLES RANDALL | 1983-05-18 | — | — | EP | disclosed |
| US-4379165-A | Anti-convulsant | RESEARCH CORPORATION (US) | 1983-04-05 | — | — | US | disclosed |
| WO-1982004046-A1 | ANTI-CONVULSANT | CLARK CHARLES RANDALL | 1982-11-25 | — | — | WO | disclosed |