Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PTPRB | P23467 | 1/20 | 0.40 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.40 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methoxymethane SCHEMBL10782344 | 0.86 | BLM (0.45) | SMN1; SMN2ALDH1A1KDM4EPOLBACACB | |
| Methoxymethane SCHEMBL10777820 | 0.86 | BLM (0.45) | SMN1; SMN2ALDH1A1KDM4EPOLBACACB | |
| SCHEMBL10779084 | 0.82 | ALDH1A1 (0.47) | SMN1; SMN2LDHAALDH1A1KDM4EPOLB | |
| SCHEMBL10779111 | 0.82 | ALDH1A1 (0.47) | SMN1; SMN2LDHAALDH1A1KDM4EPOLB | |
| SCHEMBL10535719 | 0.79 | SMN1; SMN2 (0.49) | SMN1; SMN2HTTLDHAF2RL1ALDH1A1 | |
| SCHEMBL10777945 | 0.78 | KDM4E (0.54) | SMN1; SMN2ALDH1A1KDM4EPOLB | |
| SCHEMBL16341200 | 0.77 | ACACB (0.60) | SMN1; SMN2HTTLDHAF2RL1MMP1 | |
| SCHEMBL27469291 | 0.74 | HPGD (0.47) | ALDH1A1KDM4E | |
| SCHEMBL3938137 | 0.73 | GAA (0.55) | SMN1; SMN2ALDH1A1MMP1MMP13KDM4E | |
| SCHEMBL3938131 | 0.73 | GAA (0.55) | SMN1; SMN2ALDH1A1MMP1MMP13KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4695588-A | DECARBOXYLASE INHIBITORS | MERCK & CO., INC. (US) | 1987-09-22 | — | — | US | disclosed |