Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | CTSK | P43235 | 5/20 | 0.54 |
| ▸ | CTSB | P07858 | 3/20 | 0.54 |
| ▸ | CTSL | P07711 | 2/20 | 0.54 |
| ▸ | CTSH | P09668 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.53 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.53 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10891681 | 1.00 | FAAH (0.60) | FAAHEPHX2MEN1KMT2ACTSK | |
| SCHEMBL10894372 | 1.00 | FAAH (0.60) | FAAHEPHX2MEN1KMT2ACTSK | |
| SCHEMBL10887555 | 1.00 | FAAH (0.60) | FAAHEPHX2MEN1KMT2ACTSK | |
| SCHEMBL10889910 | 1.00 | FAAH (0.60) | FAAHEPHX2MEN1KMT2ACTSK | |
| SCHEMBL10890377 | 1.00 | FAAH (0.60) | FAAHEPHX2MEN1KMT2ACTSK | |
| SCHEMBL10889447 | 1.00 | FAAH (0.60) | FAAHEPHX2MEN1KMT2ACTSK | |
| SCHEMBL622775 | 0.88 | CTSB (0.52) | FAAHEPHX2CTSKCTSBCTSL | |
| SCHEMBL622768 | 0.88 | CTSB (0.52) | FAAHEPHX2CTSKCTSBCTSL | |
| SCHEMBL24276202 | 0.86 | CNR1 (0.58) | FAAHPSMB5 | |
| SCHEMBL14341581 | 0.86 | CTSG (0.60) | CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0095295-B1 | CYCLIC PEPTIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1987-01-14 | — | — | EP | claimed |
| US-RE32311-E | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1986-12-16 | — | — | US | claimed |
| EP-0095295-A1 | Cyclic peptide derivatives | ELI LILLY AND COMPANY (US) | 1983-11-30 | — | — | EP | claimed |
| US-4396543-A | Derivatives of A-21978C cyclic peptides | ELI LILLY AND COMPANY (US) | 1983-08-02 | — | — | US | claimed |
| EP-0095295-B1 | CYCLIC PEPTIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1987-01-14 | — | — | EP | disclosed |
| US-RE32311-E | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1986-12-16 | — | — | US | disclosed |
| US-4524135-A | DEACYLATION | ELI LILLY AND COMPANY (US) | 1985-06-18 | — | — | US | disclosed |
| US-4482487-A | A-21978C cyclic peptides | ELI LILLY AND COMPANY (US) | 1984-11-13 | — | — | US | disclosed |
| EP-0095295-A1 | Cyclic peptide derivatives | ELI LILLY AND COMPANY (US) | 1983-11-30 | — | — | EP | disclosed |
| US-4396543-A | Derivatives of A-21978C cyclic peptides | ELI LILLY AND COMPANY (US) | 1983-08-02 | — | — | US | disclosed |