SCHEMBL10779103

SCHEMBL10779103

CC(=NOC(=O)c1ccccc1)C(C)=NOC(=O)c1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.62
MAPT P10636 4/20 0.60
CDK5 Q00535 3/20 0.60
CDK5R1 Q15078 3/20 0.60
PKM P14618 3/20 0.60
NPC1 O15118 5/20 0.56
RAB9A P51151 5/20 0.56
TNF P01375 1/20 0.54
KLF5 Q13887 1/20 0.54
NOD1 Q9Y239 1/20 0.54
RBBP9 O75884 1/20 0.54
TSHR P16473 1/20 0.54
F2 P00734 1/20 0.52
LMNA P02545 1/20 0.52
PLA2G7 Q13093 1/20 0.52
MITF O75030 1/20 0.51
KMT2A Q03164 2/20 0.51
ALDH1A1 P00352 2/20 0.51
XDH P47989 2/20 0.51
L3MBTL1 Q9Y468 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12328529 1.00 SMN1; SMN2 (0.62) SMN1; SMN2MAPTCDK5CDK5R1PKM
SCHEMBL194740 0.92 SMN1; SMN2 (0.59) SMN1; SMN2MAPTCDK5CDK5R1PKM
SCHEMBL194739 0.92 SMN1; SMN2 (0.59) SMN1; SMN2MAPTCDK5CDK5R1PKM
SCHEMBL195166 0.90 KMT2A (0.62) SMN1; SMN2MAPTCDK5CDK5R1PKM
SCHEMBL20278523 0.90 KMT2A (0.62) SMN1; SMN2MAPTCDK5CDK5R1PKM
SCHEMBL195165 0.90 KMT2A (0.62) SMN1; SMN2MAPTCDK5CDK5R1PKM
Acetone SCHEMBL28800731 0.89 KMT2A (0.60) SMN1; SMN2MAPTCDK5CDK5R1PKM
SCHEMBL92008 0.88 SMN1; SMN2 (0.79) SMN1; SMN2MAPTCDK5CDK5R1PKM
SCHEMBL1357956 0.86 MAPT (0.78) SMN1; SMN2MAPTCDK5CDK5R1PKM
SCHEMBL92080 0.86 MAPT (0.78) SMN1; SMN2MAPTCDK5CDK5R1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0062523-B1 DETERGENT ADDITIVE COMPOSITIONS AND PREPARATIONS AND USE THEREOF IN DETERGENT COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1987-12-09 EP disclosed
EP-0063017-B1 DETERGENT COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1986-12-10 EP disclosed
EP-0051987-B1 BLEACH ACTIVATOR COMPOSITIONS, PREPARATION THEREOF AND USE IN GRANULAR DETERGENT COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1985-04-03 EP disclosed
EP-0034387-B1 MULLS CONTAINING CHAIN STRUCTURE CLAY SUSPENSION AIDS THE PROCTER & GAMBLE COMPANY (US) 1984-10-24 EP disclosed
US-4444674-A Granular bleach activator compositions and detergent compositions containing them THE PROCTER & GAMBLE COMPANY (US) 1984-04-24 US disclosed
EP-0028432-B1 GRANULAR LAUNDRY COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1984-01-18 EP disclosed
US-4399049-A PARTICLES EXTRUDED WITH ETHOXYLATED NONIONIC SURFACTANT; STORAGE STABILITY; RABID DISPERSION; LAUNDERING THE PROCTER & GAMBLE COMPANY (US) 1983-08-16 US disclosed
EP-0063017-A1 Detergent compositions THE PROCTER & GAMBLE COMPANY (US) 1982-10-20 EP disclosed
EP-0062523-A2 Detergent additive compositions and preparations and use thereof in detergent compositions THE PROCTER & GAMBLE COMPANY (US) 1982-10-13 EP disclosed
EP-0051987-A1 Bleach activator compositions, preparation thereof and use in granular detergent compositions THE PROCTER & GAMBLE COMPANY (US) 1982-05-19 EP disclosed
US-4321157-A SILICA OR SILICATE, ORGANIC PEROXY ACID BLEACH PRECURSOR, ALIPHATIC ALCOHOL-ALKYLENE OXIDE CONDENSATE NONIONIC SURFACTANT THE PROCTER & GAMBLE COMPANY (US) 1982-03-23 US disclosed
EP-0034387-A2 Mulls containing chain structure clay suspension aids THE PROCTER & GAMBLE COMPANY (US) 1981-08-26 EP disclosed
EP-0028432-A1 Granular laundry compositions THE PROCTER & GAMBLE COMPANY (US) 1981-05-13 EP disclosed
US-4264466-A LAUNDRY DETERGENTS THE PROCTER & GAMBLE COMPANY (US) 1981-04-28 US disclosed
US-4248928-A TETRAACETYL AKYLENEDIAMINES OR TETRAACETYL GLYCOURIL PEROXY BLEACH PRECURSOR THE PROCTER & GAMBLE COMPANY (US) 1981-02-03 US disclosed
US-4179390-A Laundry additive product THE PROCTER & GAMBLE COMPANY (US) 1979-12-18 US disclosed