SCHEMBL194740

SCHEMBL194740

CC(=O)C(C)=NOC(=O)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.59
MAPT P10636 3/20 0.57
CDK5 Q00535 3/20 0.57
CDK5R1 Q15078 3/20 0.57
PKM P14618 3/20 0.57
NPC1 O15118 5/20 0.53
RAB9A P51151 5/20 0.53
TNF P01375 1/20 0.51
KLF5 Q13887 1/20 0.51
NOD1 Q9Y239 1/20 0.51
RBBP9 O75884 1/20 0.51
TSHR P16473 1/20 0.50
XDH P47989 2/20 0.49
KMT2A Q03164 2/20 0.49
ALDH1A1 P00352 1/20 0.49
MITF O75030 1/20 0.49
PLA2G7 Q13093 1/20 0.49
F2 P00734 1/20 0.48
LMNA P02545 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL194739 1.00 SMN1; SMN2 (0.59) SMN1; SMN2MAPTCDK5CDK5R1PKM
SCHEMBL12328529 0.92 SMN1; SMN2 (0.62) SMN1; SMN2MAPTCDK5CDK5R1PKM
SCHEMBL10779103 0.92 SMN1; SMN2 (0.62) SMN1; SMN2MAPTCDK5CDK5R1PKM
SCHEMBL20278523 0.87 KMT2A (0.62) SMN1; SMN2MAPTCDK5CDK5R1PKM
SCHEMBL195166 0.87 KMT2A (0.62) SMN1; SMN2MAPTCDK5CDK5R1PKM
SCHEMBL195165 0.87 KMT2A (0.62) SMN1; SMN2MAPTCDK5CDK5R1PKM
Acetone SCHEMBL28800731 0.85 KMT2A (0.60) SMN1; SMN2MAPTCDK5CDK5R1PKM
SCHEMBL92008 0.84 SMN1; SMN2 (0.79) SMN1; SMN2MAPTCDK5CDK5R1PKM
SCHEMBL92110 0.83 SMN1; SMN2 (0.57) SMN1; SMN2MAPTCDK5CDK5R1PKM
SCHEMBL1357956 0.82 MAPT (0.78) SMN1; SMN2MAPTCDK5CDK5R1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1595 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080188474-A1 e.g. 1-phenyl-N3-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-1H-1,2,4-triazole-3,5-diamine; receptor protein tyrosine kinase (AXL) antagonist; antiinflammatory, anticarcinogenic , antidiabetic agent; rheumatoid arthritis, vascular disease; breast, renal, endometrial, ovarian carcinoma, or myeloid leukemia RIGEL PHARMACEUTICALS, INC. (US) 2008-08-07 US claimed
EP-0520364-B1 Photopolymerizable composition FUJI PHOTO FILM CO LTD (JP) 1997-09-17 EP claimed
EP-0377321-B1 Photopolymerizable composition FUJI PHOTO FILM CO LTD (JP) 1995-03-22 EP claimed
US-5385807-A Photopolymerizable composition FUJI PHOTO FILM CO., LTD. (JP) 1995-01-31 US claimed
EP-0520364-A1 Photopolymerizable composition FUJI PHOTO FILM CO., LTD. (JP) 1992-12-30 EP claimed
EP-0377321-A2 Photopolymerizable composition FUJI PHOTO FILM CO., LTD. (JP) 1990-07-11 EP claimed
EP-3893054-B1 PATTERN FORMING METHOD, PHOTOSENSITIVE RESIN COMPOSITION, CURED FILM, LAMINATE, AND DEVICE FUJIFILM CORP (JP) 2026-05-06 EP disclosed
US-12609226-B2 Composition, magnetic particle-containing film, and electronic component FUJIFILM CORPORATION (JP) 2026-04-21 US disclosed
EP-3950753-B1 PHOTOSENSITIVE RESIN COMPOSITION, CURED FILM, INDUCTOR AND ANTENNA FUJIFILM CORP (JP) 2026-03-25 EP disclosed
EP-4692947-A1 CHEMICAL SOLUTION AND PATTERNING METHOD FUJIFILM Corporation (JP) 2026-02-11 EP disclosed
US-12535732-B2 Coloring composition, film, optical filter, solid-state imaging element and image display device FUJIFILM CORPORATION (JP) 2026-01-27 US disclosed
US-12529956-B2 Resin composition, film, optical filter, solid-state imaging element, and image display device FUJIFILM CORPORATION (JP) 2026-01-20 US disclosed
US-12528947-B2 Infrared-absorbing composition, film, optical filter, solid-state imaging element, image display device, and infrared sensor FUJIFILM CORPORATION (JP) 2026-01-20 US disclosed
US-5385807-A Photopolymerizable composition FUJI PHOTO FILM CO., LTD. (JP) 1995-01-31 US disclosed
EP-0300410-B1 Photopolymerizable composition MITSUBISHI CHEM IND (JP) 1994-10-26 EP disclosed
EP-0537630-A1 Photopolymerizable composition Mitsubishi Chemical Corporation (JP) 1993-04-21 EP disclosed
EP-0520364-A1 Photopolymerizable composition FUJI PHOTO FILM CO., LTD. (JP) 1992-12-30 EP disclosed
US-5049481-A Merocyanine compound FUJI PHOTO FILM CO., LTD. (JP) 1991-09-17 US disclosed
US-4966830-A Photopolymerizable composition MITSUBISHI KASEI CORPORATION (JP) 1990-10-30 US disclosed
EP-0300410-A2 Photopolymerizable composition Mitsubishi Chemical Corporation (JP) 1989-01-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12535732-B2 Coloring composition, film, optical filter, solid-state imaging element and image display device SF1, RER1, SFXN1 SMN1; SMN2 562/4885MAPT 2813/4885CDK5 4782/4885
US-12609226-B2 Composition, magnetic particle-containing film, and electronic component SMC2, SMC1A, SMC3 SMN1; SMN2 276/4885MAPT 55/4885CDK5 3312/4885
US-12529956-B2 Resin composition, film, optical filter, solid-state imaging element, and image display device PTGER1, CD40, FPR1 SMN1; SMN2 1549/4885MAPT 1954/4885CDK5 4803/4885
US-20080188474-A1 e.g. 1-phenyl-N3-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-1H-1,2,4-triazole-3,5-diamine; receptor protein tyrosine kinase (AXL) antagonist; antiinflammatory, anticarcinogenic , antidiabetic agent; rheumatoid arthritis, vascular disease; breast, renal, endometrial, ovarian carcinoma, or myeloid leukemia AXL, TYRO3, FLT3 SMN1; SMN2 4804/4885MAPT 3845/4885CDK5 384/4885
US-12528947-B2 Infrared-absorbing composition, film, optical filter, solid-state imaging element, image display device, and infrared sensor CRY2, CRY1, CHRM1 SMN1; SMN2 1733/4885MAPT 2587/4885CDK5 3796/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.