SCHEMBL92008

SCHEMBL92008

CC(C)=NOC(=O)c1ccccc1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.79
MAPT P10636 4/20 0.60
CDK5 Q00535 3/20 0.60
CDK5R1 Q15078 3/20 0.60
PKM P14618 3/20 0.60
NPC1 O15118 6/20 0.56
RAB9A P51151 6/20 0.56
TNF P01375 1/20 0.54
KLF5 Q13887 1/20 0.54
NOD1 Q9Y239 1/20 0.54
RBBP9 O75884 1/20 0.54
TSHR P16473 1/20 0.54
F2 P00734 1/20 0.52
LMNA P02545 1/20 0.52
PLA2G7 Q13093 1/20 0.52
MITF O75030 1/20 0.51
ALDH1A1 P00352 2/20 0.51
KMT2A Q03164 1/20 0.51
XDH P47989 2/20 0.51
MAPK1 P28482 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10779103 0.88 SMN1; SMN2 (0.62) SMN1; SMN2MAPTCDK5CDK5R1PKM
SCHEMBL12328529 0.88 SMN1; SMN2 (0.62) SMN1; SMN2MAPTCDK5CDK5R1PKM
SCHEMBL92080 0.86 MAPT (0.78) SMN1; SMN2MAPTCDK5CDK5R1PKM
SCHEMBL1357956 0.86 MAPT (0.78) SMN1; SMN2MAPTCDK5CDK5R1PKM
SCHEMBL194739 0.84 SMN1; SMN2 (0.59) SMN1; SMN2MAPTCDK5CDK5R1PKM
SCHEMBL194740 0.84 SMN1; SMN2 (0.59) SMN1; SMN2MAPTCDK5CDK5R1PKM
SCHEMBL20278523 0.82 KMT2A (0.62) SMN1; SMN2MAPTCDK5CDK5R1PKM
SCHEMBL195165 0.82 KMT2A (0.62) SMN1; SMN2MAPTCDK5CDK5R1PKM
SCHEMBL92110 0.82 SMN1; SMN2 (0.57) SMN1; SMN2MAPTCDK5CDK5R1PKM
SCHEMBL14667500 0.82 MAPT (0.59) SMN1; SMN2MAPTCDK5CDK5R1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 389 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0892846-B1 BLEACHING POWER ENHANCERS FOR BLEACHES AND TEXTILE WASHING COMPOSITIONS BASF AG (DE) 2002-10-23 EP claimed
US-6130198-A Bleaching efficiency boosters for bleach and textile detergent compositions BASF AKTIENGESELLSCHAFT (DE) 2000-10-10 US claimed
EP-0892846-A1 BLEACHING POWER ENHANCERS FOR BLEACHES AND TEXTILE WASHING COMPOSITIONS BASF AKTIENGESELLSCHAFT (DE) 1999-01-27 EP claimed
WO-1997035950-A1 BLEACHING POWER ENHANCERS FOR BLEACHES AND TEXTILE WASHING COMPOSITIONS BASF AKTIENGESELLSCHAFT (DE) 1997-10-02 WO claimed
EP-4658663-A2 PRODRUGS OF 4'-SUBSTITUTED NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS Merck Sharp & Dohme LLC (US) 2025-12-10 EP disclosed
CN-116601246-B Ink set, laminate, and method for producing laminate 富士胶片株式会社 2024-09-17 CN disclosed
US-20240287124-A1 PRODRUGS OF 4'-SUBSTITUTED NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS MERCK SHARP & DOHME LLC (US) 2024-08-29 US disclosed
WO-2024163262-A2 PRODRUGS OF 4'-SUBSTITUTED NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS MERCK SHARP & DOHME LLC (US) 2024-08-08 WO disclosed
CN-116601246-A Ink set, laminate, and method for producing laminate 富士胶片株式会社 2023-08-15 CN disclosed
EP-1524313-B2 MACHINE DISHWASHING COMPOSITION WITH IMPROVED RINSING PROPERTIES DALLI WERKE GMBH & CO KG (DE) 2021-12-15 EP disclosed
EP-2963495-B1 INFRARED-SENSITIVE CHROMOGENIC COMPOSITION, INFRARED-CURABLE CHROMOGENIC COMPOSITION, LITHOGRAPHIC PRINTING PLATE PRECURSOR, AND PLATE FORMATION METHOD FUJIFILM CORP (JP) 2019-06-05 EP disclosed
EP-2818522-B1 CHROMOGENIC COMPOSITION, CHROMOGENIC CURABLE COMPOSITION, LITHOGRAPHIC PRINTING PLATE PRECURSOR, PLATEMAKING METHOD, AND CHROMOGENIC COMPOUND FUJIFILM CORP (JP) 2018-11-21 EP disclosed
EP-0964912-A1 DETERGENT AND CLEANING AGENT FORMULATION WITH A BLEACHING SYSTEM AND A MIXTURE OF AMINES AND COMPLEXING AGENTS BASF AKTIENGESELLSCHAFT (DE) 1999-12-22 EP disclosed
EP-0958345-A2 ACTIVATORS FOR PER COMPOUNDS ORACLE CORPORATION (US) 1999-11-24 EP disclosed
EP-0941299-A2 TEXTILE DETERGENT FORMULATION ON THE BASIS OF QUATERNIZED GLYCINE NITRILES, BLEACHING AGENTS, NONIONIC AND/OR ANIONIC TENSIDES AND CALCIUM ION AND/OR MAGNESIUM ION SEQUESTERING COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 1999-09-15 EP disclosed
EP-0892846-A1 BLEACHING POWER ENHANCERS FOR BLEACHES AND TEXTILE WASHING COMPOSITIONS BASF AKTIENGESELLSCHAFT (DE) 1999-01-27 EP disclosed
WO-1998033878-A2 ACTIVATORS FOR PER COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 1998-08-06 WO disclosed
WO-1998032830-A1 DETERGENT AND CLEANING AGENT FORMULATION WITH A BLEACHING SYSTEM AND A MIXTURE OF AMINES AND COMPLEXING AGENTS BASF AKTIENGESELLSCHAFT (DE) 1998-07-30 WO disclosed
WO-1998023718-A2 TEXTILE DETERGENT FORMULATION ON THE BASIS OF QUATERNIZED GLYCINE NITRILES, BLEACHING AGENTS, NONIONIC AND/OR ANIONIC TENSIDES AND CALCIUM ION AND/OR MAGNESIUM ION SEQUESTERING COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 1998-06-04 WO disclosed
WO-1997035950-A1 BLEACHING POWER ENHANCERS FOR BLEACHES AND TEXTILE WASHING COMPOSITIONS BASF AKTIENGESELLSCHAFT (DE) 1997-10-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240287124-A1 PRODRUGS OF 4'-SUBSTITUTED NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS DNTT, NAPRT, NAMPT SMN1; SMN2 2653/4885MAPT 1204/4885CDK5 718/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.