Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 5/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10779282 | 1.00 | RAB9A (0.35) | RAB9AKDM4EALDH1A1PDK2APEX1 | |
| SCHEMBL11092218 | 0.78 | KDM4E (0.35) | RAB9AKDM4EALDH1A1PDK2APEX1 | |
| SCHEMBL11092216 | 0.78 | KDM4E (0.35) | RAB9AKDM4EALDH1A1PDK2APEX1 | |
| SCHEMBL10778233 | 0.77 | ALDH1A1 (0.36) | RAB9AKDM4EALDH1A1PDK2CYP1A2 | |
| SCHEMBL10778179 | 0.77 | RAB9A (0.40) | RAB9AKDM4EALDH1A1PDK2APEX1 | |
| SCHEMBL10774863 | 0.70 | RAB9A (0.39) | RAB9AKDM4EALDH1A1PDK2APEX1 | |
| SCHEMBL10778069 | 0.69 | POLB (0.34) | KDM4EALDH1A1KMT2APOLB | |
| SCHEMBL10778064 | 0.69 | POLB (0.34) | KDM4EALDH1A1KMT2APOLB | |
| SCHEMBL11089084 | 0.68 | KDM4E (0.41) | RAB9AKDM4EALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL15691586 | 0.68 | PDK2 (0.50) | RAB9AKDM4EALDH1A1PDK2APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4658061-A | ANTIARRHYTHMIC AGENTS | ELI LILLY AND COMPANY (US) | 1987-04-14 | — | — | US | disclosed |