Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10774863 | 0.80 | RAB9A (0.39) | ALDH1A1KDM4EPKMLMNARAB9A | |
| SCHEMBL10779282 | 0.77 | RAB9A (0.35) | ALDH1A1KDM4ERAB9AKMT2ACYP1A2 | |
| SCHEMBL10779288 | 0.77 | RAB9A (0.35) | ALDH1A1KDM4ERAB9AKMT2ACYP1A2 | |
| SCHEMBL10779340 | 0.75 | SLC6A4 (0.35) | ALDH1A1LMNASLC6A4HTR2AHTR2C | |
| SCHEMBL11091963 | 0.74 | GAA (0.44) | ALDH1A1KDM4EPKMLMNARAB9A | |
| SCHEMBL11089084 | 0.73 | KDM4E (0.41) | ALDH1A1KDM4EPKMLMNARAB9A | |
| SCHEMBL11092069 | 0.72 | KDM4E (0.43) | ALDH1A1KDM4EPKMLMNARAB9A | |
| SCHEMBL17445904 | 0.71 | PDK2 (0.46) | ALDH1A1KDM4EPKMLMNARAB9A | |
| SCHEMBL11235692 | 0.71 | KDM4E (0.43) | ALDH1A1KDM4EPKMLMNASLC6A4 | |
| SCHEMBL29161778 | 0.70 | PDK2 (0.39) | ALDH1A1KDM4EPKMLMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4658061-A | ANTIARRHYTHMIC AGENTS | ELI LILLY AND COMPANY (US) | 1987-04-14 | — | — | US | disclosed |