Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.76 |
| ▸ | MEN1 | O00255 | 7/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | DDX3X | O00571 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.60 |
| ▸ | PTGES | O14684 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | KDR | P35968 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6296057 | 0.86 | BAZ1A (0.74) | BAZ1AMEN1KMT2AMAPTPOLB | |
| SCHEMBL11427771 | 0.85 | MEN1 (0.62) | BAZ1AMEN1KMT2AMAPTPOLB | |
| SCHEMBL18311495 | 0.81 | MAPT (0.62) | BAZ1AMEN1KMT2AMAPTGAA | |
| SCHEMBL30469233 | 0.80 | MAPT (0.75) | MEN1KMT2AMAPTNPC1LMNA | |
| SCHEMBL4921262 | 0.80 | MAPT (0.75) | MEN1KMT2AMAPTNPC1LMNA | |
| SCHEMBL709156 | 0.80 | MEN1 (0.70) | BAZ1AMEN1KMT2AMAPTPOLB | |
| SCHEMBL11055960 | 0.79 | MEN1 (0.85) | MEN1KMT2AMAPTPOLBDDX3X | |
| SCHEMBL11433748 | 0.79 | MEN1 (0.71) | BAZ1AMEN1KMT2AMAPTPOLB | |
| SCHEMBL27880343 | 0.79 | MEN1 (0.70) | BAZ1AMEN1KMT2AMAPTPOLB | |
| SCHEMBL6302157 | 0.79 | MEN1 (1.00) | MEN1KMT2AMAPTPOLBPTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4695633-A | Chromogenic 4,4-diaryl-dihydroquinazolones, their preparation and their use | BAYER AKTIENGESELLSCHAFT (DE) | 1987-09-22 | — | — | US | disclosed |